In a nutshell This study looked at the use of focal cryotherapy (FC) for the treatment of low- to intermediate-risk prostate cancer (PC). The authors found that the use of FC was safe and increased time to further therapy with similar survival compared to active surveillance (AS). Some background PC is one of the most common forms of...
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Evaluating patient-reported outcomes with enzalutamide in the treatment of non-metastatic castration-resistant prostate cancer
In a nutshell This study evaluated patient-reported outcomes in men with non-metastatic castration-resistant prostate cancer (CRPC) when treated with either enzalutamide (Xtandi) or a placebo. The data showed that enzalutamide treatment delayed the time until pain progression and improved the quality of life of patients compared to a placebo. Some...
Read MoreEvaluating the effectiveness of tadalafil for the treatment of lower urinary tract symptoms and erectile dysfunction after low-dose-rate brachytherapy for prostate cancer
In a nutshell This study investigated the effectiveness of phosphodiesterase-5 (PDE5) inhibitor tadalafil (Cialis) for the treatment of lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) after low-dose-rate (LDR) brachytherapy (BT) in patients with localized prostate cancer. The data showed that tadalafil improved the LUTS and ED outcomes...
Read MoreUrinary, sexual outcomes and tumor control after robot-assisted laparoscopic radical prostatectomy in localized prostate cancer
In a nutshell This study analyzed the urinary, sexual, and tumor control outcomes of robotic-assisted laparoscopic radical prostatectomy (RARP) over time in patients with localized prostate cancer. The study found that analyzing these three outcomes is beneficial for these patients. Some background Localized prostate cancer (PCa) is a form of...
Read MoreSearching for patients with confined prostate cancer to trial a cryoablation procedure
In a nutshell This trial is looking to examine the use of a new treatment software (UroNAV Ablation) system in treating confined prostate cancer with cryoablation. The main outcomes to be measured will be device/treatment-related complications and tumor control. This trial is being carried out in New York, US. The details Localized...
Read MoreEvaluating the outcomes of salvage Retzius-sparing robotic-assisted radical prostatectomy
In a nutshell This study investigated the effectiveness and functional outcomes of using the Retzius-sparing robotic-assisted radical prostatectomy (RS-RARP) as a salvage treatment for patients with localized prostate cancer (PCa). The study found that the sRS-RARP approach was associated with good urinary and oncological outcomes in these...
Read MoreEvaluating long-term outcomes after high-intensity focused ultrasound for prostate cancer
In a nutshell This study evaluated the long-term outcomes of patients who underwent whole-gland high-intensity focused ultrasound (HIFU) for non-metastatic prostate cancer. The data showed that HIFU has favorable outcomes in low- and intermediate-risk groups of patients. Some background HIFU is a treatment option for prostate...
Read MoreEvaluating high-intensity focused ultrasound for prostate cancer
In a nutshell This study investigated the effect of high-intensity focused ultrasound (HIFU) on the function and outcomes of patients with localized prostate cancer (PCa). The data showed that treatment with HIFU on half of the prostate gland leads to better functional outcomes than the standard treatment. Some background...
Read MoreA look at high intensity focused ultrasound removal of prostate gland: effects and complications
In a nutshell This study investigated the short-term functional measures and complications for high-intensity focused ultrasound (HIFU) treatment in half of the prostate gland (hemi-gland) for patients with prostate cancer (PCa). The study showed that hemi-gland HIFU is a low-risk surgery and provides maintenance of sexual and urinary...
Read MoreComparing cryosurgery and hormonal therapy for locally recurrent prostate cancer after radiotherapy
In a nutshell This study compared local cryosurgery (CRYO) against androgen deprivation therapy (ADT) for the treatment of locally recurring prostate cancer (LRPC). The study found local cryosurgery had a longer overall survival (OS) when compared to ADT. Some background LRPC is cancer that has re-occurred in the prostate gland...
Read MoreThe use of relugolix in addition to radiotherapy in patients with prostate cancer
In a nutshell The study investigated the use of relugolix (Relumina), a hormonal therapy drug, in addition to radiotherapy (RT), in managing prostate cancer. The study found that relugolix was effective in reducing androgen (male sex hormones such as testosterone) levels and well tolerated in these patients. Some background Prostate...
Read MoreEvaluating the impact of long term androgen deprivation therapy and radiotherapy after prostate surgery in patients with high risk of relapse
In a nutshell The study looked at the effects of long term androgen deprivation therapy (LT-ADT), pelvic lymph node radiotherapy (PLNRT) and prostate bed radiotherapy (PBRT) in patients with prostate cancer and high risk of recurrence after prostate surgery. They found an increase in survival without cancer worsening in these patients. Some...
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