In a nutshell This study aimed to evaluate whole pelvic radiotherapy (WPRT) compared to prostate only radiotherapy (PORT) with hormonal therapy (HT) before or after radiation for patients with intermediate- or high-risk prostate cancer. This study found that HT before radiotherapy and WPRT had superior long-term survival without cancer growing or...
Read MoreCurrent stage -Stage I Posts on Medivizor
Comparing treatments for high risk localized prostate cancer
In a nutshell This study aimed to compare radiation therapy with prostate surgery used to treat prostate cancer. It found that prostate surgery had a better overall survival rate. Some background Prostate cancer can be treated using surgery or radiation therapy. Radiation therapy can be delivered externally such as external beam...
Read MoreIs conventional or hypofractionated radiation therapy better for the treatment of prostate cancer?
In a nutshell This study compared two different types of radiation therapy after prostate surgery for prostate cancer, hypofractionated postprostatectomy radiation therapy (hypoPORT) and conventional postprostatectomy radiation therapy (coPORT). Results showed that hypoPORT may be effective in prostate cancer control and with similar side effects as...
Read MoreEvaluating long-term outcomes of stereotactic body radiation therapy for low- and medium-risk prostate cancer
In a nutshell This study aimed to investigate the safety and effectiveness of stereotactic body radiation therapy (SBRT) as a treatment for prostate cancer. This study found that SBRT is a safe and effective option for low and medium risk prostate cancer. Some background Stereotactic body radiotherapy (SBRT) is a treatment option for...
Read More2018 Guidelines for the treatment of Early Stage Prostate Cancer
In a nutshell This article reviewed treatment guidelines that have been recommended for patients with early-stage prostate cancer. Some background This analysis of existing treatment guidelines was done by the leading experts in prostate cancer research. They have made recommendations on the treatment of early-stage prostate cancer. Methods...
Read MoreCan men with low-risk prostate cancer on active surveillance be monitored only by PSA and MRI?
In a nutshell This study aimed to investigate if MRI scans (a test that takes detailed images of inside the body) could safely replace biopsies (samples taken from tissues for close examination) in active surveillance for prostate cancer. This study found that men with low-risk disease can be monitored using MRI and PSA levels with selective...
Read MoreAre higher doses of radiation in less time better than conventional radiotherapy for prostate cancer?
In a nutshell This study aimed to investigate whether dose-escalated hypo-fractionated (higher doses in less time) radiation therapy would lead to better overall survival or less chance of cancer recurrence than the conventional method. They found that there is superior cancer control associated with dose-escalated hypo-fractionated radiation therapy for...
Read MoreComparing daily versus weekly imaging checks in radiation therapy for prostate cancer
In a nutshell This study aimed to investigate the best timing of treatment verification imaging used in radiation therapy for patients with prostate cancer. This study found that patients undergoing daily imaging had less risk of their cancer returning and had reduced rectal side-effects. Some background One main treatment option for prostate cancer...
Read MoreComparison between low and high dose brachytherapy followed by radiation in prostate cancer
In a nutshell The authors aimed to compare urinary symptoms in men with localized prostate cancer treated with either low-dose or high-dose rate brachytherapy in combination with radiation therapy. The authors concluded the both low-dose and high-dose brachytherapy with IMRT was safe and well-tolerated by patients. However, it took longer to recover...
Read MoreComparing the side effects of treatment options for localized prostate cancer
In a nutshell This study aimed to investigate the outcomes and side effects of radical prostatectomy, external beam radiation therapy, and active surveillance in men with localized prostate cancer. This study concluded that radical prostatectomy led to a greater decrease in sexual function and urinary continence compared to the other two treatment...
Read MoreThe timing of first biopsy and its effect on prostate cancer reclassification
In a nutshell The authors aimed to determine the influence of biopsy timing on prostate cancer reclassification during active surveillance. The authors concluded that the timing of the first biopsy was not related to an increased risk of cancer reclassification, but prostate specific antigen (PSA) and body mass index (BMI – measured based...
Read MoreBlood counts after prostate surgery can predict clinical outcomes
In a nutshell This study examined whether the neutrophil-to-lymphocyte ratio (NLR) before treatment can be used to predict clinical outcomes in localized prostate cancer. Researchers reported poorer outcomes for patients with higher NLR after surgery. Some background Neutrophils are cells that are involved in inflammation (reaction to injury or...
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