In a nutshell This study investigated the outcomes of radical prostatectomy (RP) without pelvic lymph node dissection (PLND) in patients with prostate cancer. The main finding was that 5 years after treatment, 100% of patients at low risk for cancer recurrence had survived. Some background PLND is surgery to remove the lymph nodes from the pelvis....
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Evaluating image-guided irreversible electroporation of localized prostate cancer
In a nutshell This study aimed to evaluate the use of irreversible electroporation (IRE) in the treatment of prostate cancer. This study found that IRE had low side-effect rates and promising outcomes. Some background Irreversible electroporation (IRE) uses high-energy pulses of electricity to destroy cancer cells. The brand name for...
Read MoreIs vascular-targeted photodynamic therapy or active surveillance more effective in the treatment of low-risk prostate cancer?
In a nutshell This study examined if vascular-targeted photodynamic therapy (VTPT), or active surveillance is more effective in the treatment of low-risk prostate cancer. This study concluded that patients who received VTPT were less likely to require radical therapy compared to those who underwent active surveillance. Some background...
Read MoreLooking for patients with prostate cancer to test a vaccine
In a nutshell This phase 2 trial will investigate the safety and effectiveness of a prostate cancer vaccine. The main outcome will be the rate of prostate cancer progression. The details Prostate cancer (PC) is cancer the originates in the prostate gland (PG). PC is very common, however, most men will recover from it. The progression of PC is...
Read MoreLooking for patients with advanced prostate cancer to test a type of radiation therapy
In a nutshell This trial evaluates a specific type of radiation therapy for advanced prostate cancer. The main outcome to be measured is whether or not the therapy will damage the surrounding organs. This trial is taking place in Pennsylvania, USA. The details Prostate cancer is an uncontrolled growth of the cells which make up the...
Read MoreLong-term outcomes of active surveillance for localized prostate cancer.
In a nutshell This study aimed to investigate the outcomes of active surveillance (AS) in the treatment of localized prostate cancer. This study recommends the use of AS for men with localized prostate cancer. Some background Treatments for prostate cancer often result in serious side effects such as impaired bowel, bladder or sexual functions....
Read MoreLong term results discussing radiotherapy and hormone therapy treatments for patients with prostate cancer
In a nutshell This study aimed to evaluate whole pelvic radiotherapy (WPRT) compared to prostate only radiotherapy (PORT) with hormonal therapy (HT) before or after radiation for patients with intermediate- or high-risk prostate cancer. This study found that HT before radiotherapy and WPRT had superior long-term survival without cancer growing or...
Read MoreComparing treatments for high risk localized prostate cancer
In a nutshell This study aimed to compare radiation therapy with prostate surgery used to treat prostate cancer. It found that prostate surgery had a better overall survival rate. Some background Prostate cancer can be treated using surgery or radiation therapy. Radiation therapy can be delivered externally such as external beam...
Read MoreIs conventional or hypofractionated radiation therapy better for the treatment of prostate cancer?
In a nutshell This study compared two different types of radiation therapy after prostate surgery for prostate cancer, hypofractionated postprostatectomy radiation therapy (hypoPORT) and conventional postprostatectomy radiation therapy (coPORT). Results showed that hypoPORT may be effective in prostate cancer control and with similar side effects as...
Read MoreEvaluating long-term outcomes of stereotactic body radiation therapy for low- and medium-risk prostate cancer
In a nutshell This study aimed to investigate the safety and effectiveness of stereotactic body radiation therapy (SBRT) as a treatment for prostate cancer. This study found that SBRT is a safe and effective option for low and medium risk prostate cancer. Some background Stereotactic body radiotherapy (SBRT) is a treatment option for...
Read More2018 Guidelines for the treatment of Early Stage Prostate Cancer
In a nutshell This article reviewed treatment guidelines that have been recommended for patients with early-stage prostate cancer. Some background This analysis of existing treatment guidelines was done by the leading experts in prostate cancer research. They have made recommendations on the treatment of early-stage prostate cancer. Methods...
Read MoreCan men with low-risk prostate cancer on active surveillance be monitored only by PSA and MRI?
In a nutshell This study aimed to investigate if MRI scans (a test that takes detailed images of inside the body) could safely replace biopsies (samples taken from tissues for close examination) in active surveillance for prostate cancer. This study found that men with low-risk disease can be monitored using MRI and PSA levels with selective...
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