In a nutshell This study evaluated the long-term outcomes of patients who underwent whole-gland high-intensity focused ultrasound (HIFU) for non-metastatic prostate cancer. The data showed that HIFU has favorable outcomes in low- and intermediate-risk groups of patients. Some background HIFU is a treatment option for prostate...
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Evaluating high-intensity focused ultrasound for prostate cancer
In a nutshell This study investigated the effect of high-intensity focused ultrasound (HIFU) on the function and outcomes of patients with localized prostate cancer (PCa). The data showed that treatment with HIFU on half of the prostate gland leads to better functional outcomes than the standard treatment. Some background...
Read MoreA look at high intensity focused ultrasound removal of prostate gland: effects and complications
In a nutshell This study investigated the short-term functional measures and complications for high-intensity focused ultrasound (HIFU) treatment in half of the prostate gland (hemi-gland) for patients with prostate cancer (PCa). The study showed that hemi-gland HIFU is a low-risk surgery and provides maintenance of sexual and urinary...
Read MoreComparing cryosurgery and hormonal therapy for locally recurrent prostate cancer after radiotherapy
In a nutshell This study compared local cryosurgery (CRYO) against androgen deprivation therapy (ADT) for the treatment of locally recurring prostate cancer (LRPC). The study found local cryosurgery had a longer overall survival (OS) when compared to ADT. Some background LRPC is cancer that has re-occurred in the prostate gland...
Read MoreThe use of relugolix in addition to radiotherapy in patients with prostate cancer
In a nutshell The study investigated the use of relugolix (Relumina), a hormonal therapy drug, in addition to radiotherapy (RT), in managing prostate cancer. The study found that relugolix was effective in reducing androgen (male sex hormones such as testosterone) levels and well tolerated in these patients. Some background Prostate...
Read MoreEvaluating the impact of long term androgen deprivation therapy and radiotherapy after prostate surgery in patients with high risk of relapse
In a nutshell The study looked at the effects of long term androgen deprivation therapy (LT-ADT), pelvic lymph node radiotherapy (PLNRT) and prostate bed radiotherapy (PBRT) in patients with prostate cancer and high risk of recurrence after prostate surgery. They found an increase in survival without cancer worsening in these patients. Some...
Read MoreDoes the frequency of radiotherapy doses impact its effectiveness and safety for patients with localized prostate cancer?
In a nutshell This study examined if the frequency of the same dose of radiotherapy (RT) changed the effectiveness and safety of patients with localized prostate cancer (PC). The results showed that RT that was given weekly was as effective and safe as RT given every other day. Some background Radiotherapy (RT) is an effective treatment for...
Read MoreDoes surgical treatment of early prostate cancer reduce mortality in the long run compared to watchful waiting?
In a nutshell The study compared the long-term outcomes of prostate surgery (radical prostatectomy; RP) and observation (watchful waiting; WW) in patients with early prostate cancer. The study showed that surgery reduced mortality in these patients. Some background Prostate cancer is one of the most common cancers in American men....
Read MoreSearching for patients to try a radiation treatment strategy for prostate cancer.
In a nutshell This trial is examining the effectiveness of ultra-high-dose hypofractionated or single-dose radiotherapy for intermediate (medium) risk prostate cancer. The main outcome that will be measured will be the number of patients that experience side effects. This study is being conducted in New York City, NY, the US. The details...
Read MoreWhat are the effects of radical prostatectomy without pelvic lymph node dissection in prostate cancer?
In a nutshell This study investigated the outcomes of radical prostatectomy (RP) without pelvic lymph node dissection (PLND) in patients with prostate cancer. The main finding was that 5 years after treatment, 100% of patients at low risk for cancer recurrence had survived. Some background PLND is surgery to remove the lymph nodes from the pelvis....
Read MoreEvaluating image-guided irreversible electroporation of localized prostate cancer
In a nutshell This study aimed to evaluate the use of irreversible electroporation (IRE) in the treatment of prostate cancer. This study found that IRE had low side-effect rates and promising outcomes. Some background Irreversible electroporation (IRE) uses high-energy pulses of electricity to destroy cancer cells. The brand name for...
Read MoreIs vascular-targeted photodynamic therapy or active surveillance more effective in the treatment of low-risk prostate cancer?
In a nutshell This study examined if vascular-targeted photodynamic therapy (VTPT), or active surveillance is more effective in the treatment of low-risk prostate cancer. This study concluded that patients who received VTPT were less likely to require radical therapy compared to those who underwent active surveillance. Some background...
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