In a nutshell The study evaluated the link between statin (cholesterol-lowering drugs) use and risks of breast cancer (BC) relapse under adjuvant aromatase inhibitors (AI) therapy in women after their menopause. The main finding was that statin use was related with lower risks of BC relapse in such patients. Some background Women with...Read More
Current stage-Stage I Posts on Medivizor
Does chemotherapy and SBRT improve survival in older patients with early stage non-small cell lung cancer (NSCLC)?
In a nutshell This study investigated chemotherapy (CT) and stereotactic body radiotherapy (SBRT) in older patients with early-stage non-small cell lung cancer (NSCLC). They found that CT after SBRT improved survival in older patients with tumors greater than 4 cm. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung...Read More
In a nutshell This study looked at fertility preservation (FP) in patients with breast cancer. It found that many patients choose FP before chemotherapy and that most patients have a return of ovulation following treatment. Some background 12% of patients newly diagnosed with breast cancer are under 40 years of age. Preserving fertility is a concern...Read More
In a nutshell This study examined the effectiveness of hormonal therapy in premenopausal women with hormone receptor-positive early breast cancer with or without other treatments. The authors concluded that patients who received hormonal therapy had a higher chance of survival and without a return of cancer. Some background The hormone...Read More
In a nutshell This paper is a document that was developed at a breast cancer conference by a number of experts in the field. It outlines suggested treatment for early-stage breast cancer. The experts concluded that patients and doctors should work together and discuss the benefit of treating early-stage breast cancer in comparison with the potential...Read More
In a nutshell This study reviewed the effect of follow-up programs on the survival of patients with colorectal cancer. Researchers suggested that intense follow-up programs do not improve the survival of these patients. Some background Colorectal cancer is a commonly diagnosed cancer in the US. Two in three patients will present with the possibly...Read More
In a nutshell This study investigated the effects of complete mesocolic excision (CME) in patients with right-side colon cancer. Researchers suggested that CME reduces the risk of recurrences (when cancer comes back) in these patients. Some background Colorectal cancer is one of the most common cancers worldwide. The standard treatment is surgery and...Read More
In a nutshell This study aimed to compare the outcomes for patients with early breast cancer who received 6- or 12-months trastuzumab after surgery. This study concluded that the standard duration of trastuzumab after surgery should remain 12 months. Some background Trastuzumab (Herceptin) is a targeted...Read More
Comparing letrozole and taselisib against letrozole and placebo before surgery in early stage breast cancer
In a nutshell This study aimed to investigate the combination of letrozole and taselisib as a neoadjuvant treatment (before surgery) in patients with hormone receptor-positive, HER2-negative, early stage breast cancer. This study concluded that this treatment...Read More
In a nutshell This study aimed to investigate the effectiveness and safety of talazoparib as a neoadjuvant agent (treatment before surgery) in patients with BRCA mutation and operable breast cancer. This study concluded that this treatment was a safe and effective in these patients. Some...Read More
In a nutshell This study investigated the effectiveness of local vs radical surgery in patients with rectal cancer. Researchers suggested that local surgery is associated with better outcomes in certain patients with early cancers. Some background Colorectal cancer is the third most common cancer in the US. The standard treatment options for these...Read More
Chemotherapy before breast conserving surgery in breast cancer – is there an increased risk of complications?
In a nutshell This study investigated the effect of neoadjuvant chemotherapy (NAC; chemotherapy before surgery) in patients undergoing oncoplastic breast-conserving surgery (OBCS). They found that NAC did not affect the rate of complications in OBCS. Some background Breast cancer (BC) can be treated using a number of strategies....Read More