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Phase 3 clinical trial comparing the addition of anastrozole versus tamoxifen to goserelin therapy before surgery for patients with early-stage breast cancer

Phase 3 clinical trial comparing the addition of anastrozole versus tamoxifen to goserelin therapy before surgery for patients with early-stage breast cancer

Posted by on Jun 5, 2013 in Breast cancer | 0 comments

In a nutshell This phase 3 clinical trial compared the safety and efficacy of two different combination treatments in women with early stage breast cancer: anastrozole (Arimidex) plus goserelin (Zoladex) versus tamoxifen (Nolvadex) plus goserelin. Some background An estrogen-receptor positive (ER+) breast cancer requires estrogen (the primary...

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Predicting residual or recurrent disease in patients with invasive colorectal adenocarcinoma developed from colorectal adenoma treated by endoscopy?

Predicting residual or recurrent disease in patients with invasive colorectal adenocarcinoma developed from colorectal adenoma treated by endoscopy?

Posted by on Apr 10, 2013 in Colorectal cancer | 0 comments

In a nutshell The present study evaluated factors associated with residual or recurrent disease in patients with colorectal adenocarcinomas developed from adenomas initially treated endoscopically. Some background A colorectal adenoma is a benign (non-cancerous) abnormal growth in the inner lining of the large intestine (colon and rectum) also...

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The cancer rate among patients who were treated surgically for polyps that were impossible to remove endoscopically

Posted by on Mar 17, 2013 in Colorectal cancer | 0 comments

In a nutshell This study aimed to determine the rate of cancer cases in patients with polyps that were removed surgically. Factors that predict the presence of cancer in these polyps were also investigated. The results confirm the fact that the best therapeutic option for polyps that cannot be removed endoscopically is radical surgery. Some background...

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Surgical options for the management of cancerous colonic polyps: surgery versus colonoscopic removal

Posted by on Mar 10, 2013 in Colorectal cancer | 0 comments

In a nutshell The present study compared the results of two surgical techniques for the removal of cancerous colonic polyps: surgical resection versus colonoscopic polypectomy.  Some background Most colorectal cancers develop from a malignant (cancerous) polyp, an abnormal growth on the inner surface of the large intestine. When a polyp is...

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Surveillance colonoscopy is performed early in patients who undergo curative surgery for colorectal cancer

Posted by on Mar 10, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated how surveillance colonoscopies (SC) were used in colorectal cancer patients previously treated with surgery. The main finding was that many patients who had curative surgery (complete removal of the cancer) underwent SC more often than recommended by the guidelines. Some background Patients who undergo curative...

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The impact of radiotherapy protocol on quality of life in patients with operable rectal cancer

The impact of radiotherapy protocol on quality of life in patients with operable rectal cancer

Posted by on Mar 3, 2013 in Colorectal cancer | 0 comments

In a nutshell This article evaluated the long-term quality of life of patients with rectal cancer, treated with either a short course of radiation before surgery, or postoperative chemo-radiation. Patients treated with pre-operative radiation reported worse sexual- and bowel-related functional outcomes.   Some background In patients with...

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Personalizing breast cancer treatment based on the genetic “finger-print” of the tumor

Personalizing breast cancer treatment based on the genetic “finger-print” of the tumor

Posted by on Feb 25, 2013 in Breast cancer | 0 comments

This article discusses how tests such as the Oncotype DX or Mammaprint can be used to design individual treatment plans for patients with breast cancer. Patients with stage I and stage II breast cancer are treated similarly. Following surgical removal of a breast tumor, systemic (body-wide) treatment is often used.  This secondary treatment is...

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