In a nutshell This study examined the benefit of combining radiation therapy with androgen deprivation therapy (ADT) in older men and in men with aggressive cancer cells. Researchers reported reduced mortality risks with combination therapy in all groups studied. Some background Radiation therapy is a common treatment for localized...
Read MoreCurrent PSA level-Between 10 to 20 Posts on Medivizor
Searching for men with early stage prostate cancer to test a short course of very focused radiation therapy
In a nutshell This phase 1/2 trial aims to evaluate the effectiveness of a short course of very focused radiation therapy in the treatment of early stage prostate cancer. The main outcome to be investigated is side effects and treatment response. The trial is recruiting in San Diego, California (USA). The details External beam radiation therapy...
Read MoreLocalized prostate cancer: Prostate surgery and radiation therapy compared
In a nutshell This study examined the effectiveness of various treatment combinations for localized prostate cancer. Researchers concluded that prostate surgery is as effective as radiation therapy, but without the need for additional hormone therapy. Some background Surgical removal of the prostate gland and radiation therapy are both...
Read MoreShould hormone therapy be added to intensive radiotherapy in early prostate cancer?
In a nutshell This study examined the potential benefit of early hormone therapy added to intensive radiotherapy in the treatment of men with intermediate-risk local prostate cancer. Overall survival was found to be improved with higher radiation dosage. However, the researchers noted that early hormone therapy does generally not benefit treatment...
Read MoreCombined androgen blockade before surgery for local cancers
In a nutshell This study examined the potential benefit of early intensive hormonal therapy (combined androgen blockade) in men with high-risk local prostate cancer, given before surgery. Researchers concluded that intensive hormone therapy may be more effective than standard treatment in reducing androgen levels, but seldom results in complete tumor...
Read MoreLooking for patients with metastatic hormone-resistant prostate cancer to evaluate the benefit of using immunotherapy and radiation
In a nutshell This phase II trial based in Dallas, Texas aims to determine the effect of immunotherapy and stereotactic ablative body radiation as a metastatic hormone-resistant prostate cancer treatment. The main outcome to be investigated is time from treatment until cancer progression. The details Metastatic prostate cancer is cancer that...
Read MoreLooking for prostate cancer patients who have had their prostate removed to determine the safety of a shorter course of radiation
In a nutshell This phase I/II trial aims to determine the safety of administering shorter courses of radiation over a shorter period of time to patients who have had their prostate removed. The main outcome to be investigated is dose safety and toxicity in patients and to determine quality of life benefits. The details Radiation therapy...
Read MoreThe benefit of taxanes in hormone-resistant prostate cancer
In a nutshell The authors aimed to determine the effects of taxanes when treating prostate cancer patients with hormone-resistant cancer. Some background Hormone therapy is a common prostate cancer treatment. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients may become hormone-resistant....
Read MoreThe effect of standard treatments in patients with favorable and unfavorable prostate cancer
In a nutshell The authors aimed to determine the effect of common treatments on prostate cancer-specific mortality for patients with intermediate-risk prostate cancer. Some background Intermediate-risk prostate cancer is cancer that has grown through and/or out of the prostate. It can be further classified as favorable or...
Read MoreCan hormone treatment decrease the risk of prostate cancer recurrence?
In a nutshell The authors aimed to determine whether hormone therapy had an effect on biochemical failure and cancer spread in prostate cancer patients undergoing radiation therapy. Some background Intermediate-risk prostate cancer is cancer that requires active treatment due to growth through and/or out of the prostate. It can be treated...
Read MoreIdentifying prostate cancer progression
In a nutshell The authors aimed to identify the best options available to identify metastatic prostate cancer. Some background Metastatic prostate cancer is cancer that has spread from the prostate gland into tissues and organs around the body. In some cases patients with metastatic cancer can become resistant to certain treatments, such as...
Read MoreComparing urinary incontinence and erectile dysfunction as side effects after robotic vs. open prostate removal
In a nutshell This study aimed to evaluate the complications associated with robotic-assisted prostate removal (minimally invasive) compared to an open surgical procedure (more invasive). Some background Open surgical removal of the prostate has previously been the traditional surgical approach for prostate cancer treatment. Robot-assisted...
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