In a nutshell This Phase II (early phase) study aimed to evaluate the safety and side effects of GTx-758, a drug that is being researched as a therapy for lowering testosterone levels in the blood stream. Some background Androgen-deprivation therapy (ADT – a form of hormone therapy that lowers testosterone levels) remains the most...
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In a nutshell The authors aimed to determine the effects of focal therapy on prostate cancer patient outcome. Some background Index lesion focal therapy is a form of non-invasive treatment that uses energy to target a specific region of the prostate that contains cancer, causing minimal damage to healthy tissue and less-severe side-effects...
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In a nutshell The authors aimed to determine patient and cancer outcome following treatment with pelvic lymph node dissection and robot-assisted prostate surgery. Some background In some prostate cancer patients tumors can spread into the lymph nodes (sites that hold cells used to fight infection). A pelvic lymph node dissection is used to...
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In a nutshell The authors aimed to determine patient outcome after salvage prostate surgery using patient information. Some background Prostate surgery is a common cancer treatment that involves surgically removing the prostate gland. Salvage prostate surgery is carried out after radiation therapy (involves directing a beam of radiation at the...
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In a nutshell The authors aimed to determine whether statin use can prevent prostate cancer recurrence after brachytherapy. Some background Brachytherapy is a form of radiation, where a radiation source is internally placed at the tumor site. It is sometimes given in combination with external beam radiation therapy (EBRT – radiation...
Read MoreIn a nutshell This study identified risk factors in high-risk prostate cancer patients that could influence the success of radical prostatectomy (RP). Some background Prostate cancer is a cancer of the prostate gland that makes up part of the male reproductive system. Though the majority of men will not die from this cancer, some forms can be...
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In a nutshell The authors evaluated whether robot-assisted surgery, in patients with high-risk prostate cancer, compares well to other surgical technique. Some background One treatment option for patients with high-risk prostate cancer is surgical removal of the prostate (radical prostatectomy). Three different surgical techniques can be used for...
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In a nutshell This study evaluated long-term mortality with intermediate-risk prostate cancer and the significance of favorable versus unfavorable prognostic factors in the selection of the most appropriate therapy. Some background Men newly diagnosed with prostate cancer are initially stratified into three risk groups based on low, intermediate,...
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In a nutshell This study evaluated the use of multi-parametric magnetic resonance imagining (MRI) in the selection of prostate cancer patients for active surveillance. Some background Active surveillance was introduced as a therapeutic strategy to avoid overtreatment of cancer patients with a relatively non-threatening disease. In active...
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In a nutshell This review evaluated the safety and efficacy of focal salvage ablative therapy for the treatment of patients with prostate cancer recurrence (return of the cancer) after radiation therapy. Some background Radiation therapy (RT) is often used to treat early stage prostate cancer. However, after RT, the cancer may recur, locally...
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In a nutshell This review investigated treatment options following biochemical recurrence after primary treatment for prostate cancer. Some background Prostate cancer can be treated using a variety of methods, the most common being partial or full removal of the prostate gland, a procedure known as a prostatectomy. Other treatments include...
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In a nutshell The study evaluated whether active surveillance (AS) is a safe approach and can prevent over-treatment in patients with prostate cancer. Some background In the recent years, survival rates for prostate cancer patients have increased due to more advanced screening methods, which allow for early detection and prevention of...
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