In a nutshell This study investigated whether age affected disease progression or survival rates in patients with late stage colorectal cancer. Some background The average age at diagnosis of colorectal cancer (CRC) is 72 years. 28% of diagnoses are made in people aged over 80. Only 4.6% are made in those aged under 50. Younger CRC patients tend...
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How often are bisphosphonates required in breast cancer that has spread to the bone?
In a nutshell The authors aimed to evaluate the benefit of reducing the dosage of bisphosphonate therapy (such as Fosamax or Reclast) for women with bone metastasis (the original cancer has spread to the bones). Some background Bisphosphonate therapy is a treatment used to prevent the loss of bone mass. Women who have developed bone...
Read MoreReview of advanced prostate cancer treatments
In a nutshell The authors analyzed treatment options available for advanced prostate cancer. Some background At the first St. Gallen Advanced Prostate Cancer Conference leading experts met to determine the most up-to-date guidelines for the treatment of advanced prostate cancer. Advanced prostate cancer is cancer that has spread...
Read MorePossible new treatment for metastatic breast cancer
In a nutshell The authors aimed to determine the effectiveness and safety adding bevacizumab (Avastin) to a chemotherapy regimen in previously treated patients with metastatic (spread to other areas of the body) breast cancer. Some background Metastasis is the spread of cancer to other organs in the body. Patients with metastatic...
Read MoreDocetaxel treatment improves patient survival in metastatic prostate cancer
In a nutshell The authors determined the benefit of docetaxel (Taxotere) and prednisone (Deltasone) in treating metastatic (cancer that spreads) hormone-resistant prostate cancer. Some background Hormone therapy is a common treatment for prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. In...
Read MoreTreating advanced non-small cell lung cancer – is gefitinib the solution?
In a nutshell This study looked at a new drug, gefitinib (Iressa), used for treating non-small cell lung cancer (NSCLC) that has spread from its original site. Some background A common treatment option for non-small cell lung cancer is chemotherapy. Many patients find the side effects of this treatment to be quite severe. The long-term outcomes...
Read MoreCan radiofrequency ablation control adrenal tumors?
In a nutshell This study looked at whether a treatment known as radiofrequency ablation is useful in treating cancer which has spread to a patient’s adrenal glands. Some background The adrenal glands sit on top of the kidneys and make several hormones for the body. Chemotherapy or radiotherapy are often used to treat cases where...
Read MoreCan radiofrequency ablation control adrenal tumors?
In a nutshell This study looked at whether a treatment known as radiofrequency ablation is useful in treating cancer which has spread to a patient’s adrenal glands. Some background The adrenal glands sit on top of the kidneys and make several hormones for the body. Chemotherapy or radiotherapy are often...
Read MoreEnzalutamide – a new treatment for improving prostate cancer outcomes
In a nutshell The authors interpreted the results of a phase III trial on the use of enzalutamide (Xtandi) in treating patients with metastatic (cancer that has spread) hormone-resistant (castration-resistant) prostate cancer. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones...
Read MoreDo beta-blockers reduce the risk of prostate cancer death?
In a nutshell The authors determined the association between beta-blockers and prostate cancer-specific mortality (patients who died from prostate cancer following treatment) in patients with high-risk (stage IV) or metastatic (cancer spread out from prostate) cancer. Some background Hormone therapy is a common treatment used in prostate...
Read MoreBenefits of surgery in advanced melanoma with liver metastasis
In a nutshell The authors evaluated melanoma patients with liver metastasis (spread of cancer from the skin to liver) undergoing surgery or other treatments. Some background In advanced melanoma (stage IV), cancer often spreads from the skin to the liver. There are two treatment options in liver metastasis – surgery and...
Read MoreAbiraterone acetate in metastatic hormone-resistant prostate cancer
In a nutshell The authors determined the safety and effectiveness of abiraterone acetate (Zytiga) in patients with metastatic hormone-resistant prostate cancer. Some background Hormone therapy is a common treatment used in prostate cancer. It targets the male sex hormones active in prostate cancer, such as testosterone. Some patients...
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