In a nutshell This study examined the safety and effects of minimally invasive prostate surgery in older men with localized (confined) prostate cancer. Researchers reported similar outcomes of minimally invasive prostate surgery in older patients and in younger patients. Some background Prostate surgery is a first-line treatment for localized...
Read MoreIn a nutshell This study compared the side effects of external beam radiation therapy (EBRT) and hypofractioned EBRT (H-EBRT) on erectile and sexual function. Researchers reported similar effects of EBRT and H-EBRT on erectile and sexual function up to 3 years after treatment. Some background Radiation therapy is a common treatment for localized...
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In a nutshell This study aimed to determine whether EGFR-TKIs, in combination with surgery, is beneficial to patients with operable non-small-cell lung cancer (NSCLC). The authors concluded that patients with EGFR-mutation-positive NSCLC who were treated with both surgery and EGFR-TKIs showed improved survival compared to patients who underwent surgery...
Read MoreIn a nutshell This study compared prostate surgery and radiation therapy in treating high-risk prostate cancer. Authors reported similar survival benefits with both treatments. However, high doses of total radiation combined with hormone therapy was associated with the lowest risk of disease progression. Some background Prostate surgery and...
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In a nutshell This study examined the evidence for combining androgen deprivation therapy (ADT) with radiation therapy for the treatment of high-risk localized prostate cancer. Authors concluded that the combined therapy approach was associated with a survival advantage for intermediate- and high-risk patients. Some background ADT is a type...
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In a nutshell This study investigated the optimal waiting time between radiation therapy and surgery in rectal cancer patients. Researchers suggested that a prolonged waiting time is associated with tumor shrinkage. Some background Surgery is the only curative treatment for rectal cancer. Chemotherapy and radiation therapy is the recommended...
Read MoreIn a nutshell This study compared the safety and effectiveness of two forms of imaging-guided radiation techniques for prostate cancer. Researchers reported more favorable outcomes with intensity modulated radiation therapy (IMRT) than with 3-dimensional conformal radiation therapy (3DCRT). Some background Radiation therapy is a common treatment...
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In a nutshell This study examined the benefit of adding apalutamide (JNJ 56021927) to standard hormone therapy in men with castration-resistant prostate cancer (CRPC). Researchers reported preliminary evidence for apalutamide as a safe and effective additional hormone therapy for high-risk CRPC. Some background Hormone therapy is the standard of...
Read MoreIn a nutshell This study evaluated prostate-specific mortality risk based on PSA (prostate specific antigen) levels in men with high-grade disease. Authors reported increased mortality risk with lower PSA levels in men with high-grade disease. A decreased mortality risk was observed with lower PSA levels in men with low-grade disease. Some background...
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In a nutshell This study examined robotic assisted radical prostatectomy (RARP) in the treatment of high-risk localized prostate cancer. Researchers reported that the number of risk factors did not increase the risk of cancer recurrence after RARP. Some background Prostate surgery (also called radical prostatectomy) is a common treatment for...
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In a nutshell This study investigated erectile function after prostate surgery in men with high-risk localized prostate cancer. Researchers reported high rates of erectile dysfunction following prostate surgery. Some background Surgical removal of the prostate gland is a common treatment for localized prostate cancer (cancer confined to the...
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In a nutshell This study compared intermittent and continuous androgen deprivation therapy (ADT) in treating locally advanced prostate cancer. Researchers reported that both intermittent and continuous ADT were equally as effective and well-tolerated. Some background ADT is a type of hormone therapy that blocks male hormones (such as testosterone)...
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