In a nutshell The study analyzed outcomes of high-dose therapy (HDT) with autologous hematopoietic stem cell transplantation (AHSCT) for patients with non-Hodgkin lymphoma (NHL) in a resource-limited country and evaluated whether upfront AHSCT could be an effective treatment. The authors found promising outcomes of this treatment in a resource-limited...
Read MoreCurrent disease status-First occurrence of the lymphoma Posts on Medivizor
Evaluating treatment options for pregnant patients with non-Hodgkin lymphoma
In a nutshell This study was carried out to assess the outcomes of pregnant women who have non-Hodgkin lymphoma (NHL). The authors concluded that treating NHL with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone)-like regimens during pregnancy can be considered after the first trimester. Some background NHL...
Read MoreDoes first-line treatment with R-CHOP benefit patients with grade 3A follicular lymphoma?
In a nutshell This study aimed to compare the effectiveness of 2 drug regimens for patients with grade 3A follicular lymphoma (FL3A). The authors concluded that R-CHOP has a benefit over RB in the treatment of these patients. Some background Follicular lymphoma (FL) is the most common type of non-Hodgkin lymphoma (NHL).FL usually has good...
Read MoreHow does ABVD chemotherapy affect the fertility of female patients with Hodgkin lymphoma?
In a nutshell This study examined if ABVD chemotherapy impacted fertility in female patients with Hodgkin lymphoma (HL). The authors found that ABVD reduced the levels of one of the fertility hormones and the type of fertility treatment patients opted for was not affected by ABVD. Some background Many patients with HL are young and fertility...
Read MoreWhich patients with diffuse large B cell lymphoma benefit most from CAR-T treatment?
In a nutshell This study compared the effectiveness of CAR-T treatment for patients with diffuse large B cell lymphoma (DLBCL). The authors found that while a significant number of all patients benefitted from the treatment, some patients were more likely to benefit from it than others. Some background During initial treatment for DLBCL,...
Read MoreHow effective and safe is high-dose chemotherapy and stem cell transplant for children with lymphoma?
In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) have very...
Read MoreHow effective and safe is high-dose chemotherapy and stem cell transplant for children with lymphoma?
In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL)...
Read MoreCurrent treatment for advanced classical Hodgkin lymphoma
In a nutshell This review summarizes current treatment options of advanced classical Hodgkin lymphoma. It found that PET-scan based treatment minimizes long-term side effects and that both ABVD and eBEACOPP are useful chemotherapy regimens. Some background Classical Hodgkin lymphoma (cHL) is a cancer of white blood cells. If cancerous...
Read MoreEvaluating BEB chemotherapy for patients with non-Hodgkin’s lymphoma
In a nutshell This study evaluated the safety and effectiveness of BEB (busulfan, etoposide, bendamustine) chemotherapy for patients with non-Hodgkin’s lymphoma (NHL). This study found that BEB chemotherapy was effective and well-tolerated in these patients. Some background Autologous stem cell transplantation (ASCT) is a standard...
Read MoreEvaluating an antibody therapy for recurrent or non-responding NHL
In a nutshell This study evaluated the safety and effectiveness of loncastuximab tesirine (LT) for recurrent or non-responding non-Hodgkin’s lymphoma (NHL). This study found that LT showed promising effectiveness, with manageable side effects. Some background Patients with NHL often receive strong treatment to kill cancer cells. 60 to 70%...
Read MoreIs R-CVP safer and more effective than R-CHOP for patients with painless NHL?
In a nutshell This study evaluated the safety and effectiveness of two different chemotherapy regimens for patients with indolent (painless) non-Hodgkin’s lymphoma (NHL). This study found that the R-CVP regimen was similarly effective and had fewer side effects compared to R-CHOP for these patients. Some background Chemoimmunotherapy is the...
Read MoreAre prognostic scores still useful for predicting outcomes for patients with advanced Hodgkin’s lymphoma?
In a nutshell This study examined if international prognostic scores (IPS) could help predict treatment outcomes for patients with advanced Hodgkin's lymphoma (HL). The authors found that the IPS system is losing its predictability as treatment strategies improve for these patients. Some background Patients with HL need to be treated...
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