In a nutshell This study evaluated the safety and effectiveness of BEB (busulfan, etoposide, bendamustine) chemotherapy for patients with non-Hodgkin’s lymphoma (NHL). This study found that BEB chemotherapy was effective and well-tolerated in these patients. Some background Autologous stem cell transplantation (ASCT) is a standard...
Read MoreCurrent disease status-First occurrence of the lymphoma Posts on Medivizor
Evaluating an antibody therapy for recurrent or non-responding NHL
In a nutshell This study evaluated the safety and effectiveness of loncastuximab tesirine (LT) for recurrent or non-responding non-Hodgkin’s lymphoma (NHL). This study found that LT showed promising effectiveness, with manageable side effects. Some background Patients with NHL often receive strong treatment to kill cancer cells. 60 to 70%...
Read MoreIs R-CVP safer and more effective than R-CHOP for patients with painless NHL?
In a nutshell This study evaluated the safety and effectiveness of two different chemotherapy regimens for patients with indolent (painless) non-Hodgkin’s lymphoma (NHL). This study found that the R-CVP regimen was similarly effective and had fewer side effects compared to R-CHOP for these patients. Some background Chemoimmunotherapy is the...
Read MoreAre prognostic scores still useful for predicting outcomes for patients with advanced Hodgkin’s lymphoma?
In a nutshell This study examined if international prognostic scores (IPS) could help predict treatment outcomes for patients with advanced Hodgkin's lymphoma (HL). The authors found that the IPS system is losing its predictability as treatment strategies improve for these patients. Some background Patients with HL need to be treated...
Read MoreTreatment approaches for patients with advanced Hodgkin’s lymphoma
In a nutshell This article reviewed different treatment approaches for patients with advanced Hodgkin's lymphoma (HL). Some background HL is a type of blood cancer of the lymphatic system. HL can be classified in different ways. In limited HL, cancer is found in one or two sites in the lymphatic system. In advanced HL, cancer is found on...
Read MoreEvaluating combined modality treatment for young adults with Hodgkin lymphoma
In a nutshell This study determined the safety and effectiveness of combined modality treatment for young adults with classical Hodgkin lymphoma (cHL). This study concluded that this treatment approach was well-tolerated and effective for these patients. Some background Chemotherapy regimens for pediatric patients with cHL are different from...
Read MoreEvaluating pembrolizumab for patients with primary mediastinal large B-cell lymphoma that has come back or stopped responding to treatment
In a nutshell This study evaluated the safety and effectiveness of pembrolizumab (Keytruda) for patients with primary mediastinal large B-cell lymphoma (PMBCL) that has come back or stopped responding to treatment. This study concluded that pembrolizumab was safe and effective for these patients. Some background PMBCL is one rare and aggressive type...
Read MoreHow does maintenance therapy affect quality of life for patients with DLBCL?
In a nutshell This study evaluated lenalidomide (Revlimid) maintenance therapy versus placebo for patients with diffuse large B-cell lymphoma (DLBCL). The authors found that lenalidomide increased the number of side effects but did not impact health status. Some background DLBCL is an aggressive type of non-Hodgkin's lymphoma....
Read MoreEvaluating subcutaneous rituximab for patients with non-Hodgkin lymphoma
In a nutshell This study examined whether it is safe to switch from intravenous to subcutaneous rituximab (Rituxan) during first-line treatment of non-Hodgkin's lymphoma (NHL). The authors concluded that subcutaneous rituximab was safe and effective, and improved quality of life for patients. Some background Rituximab is a standard...
Read MoreWhat factors can predict the success of stem cell transplantation for patients with lymphoma?
In a nutshell This study evaluated the risk factors associated with delayed engraftment in patients who had stem cell transplantation (SCT). The authors found that patients receiving blood transfusions, those with low platelet levels, and those given low numbers of stem cells during SCT were more likely to experience DE. Some...
Read MoreEvaluating brentuximab vedotin for patients with relapsed or unresponsive Hodgkin lymphoma after SCT
In a nutshell This study compared the effectiveness of brentuximab vedotin (Adcetris) to chemotherapy in patients with classical Hodgkin’s lymphoma (cHL) that came back or stopped responding after a stem cell transplant (SCT). This study concluded that patients treated with brentuximab vedotin had better outcomes compared to patients in the...
Read MoreLymphoma transformation risk in patients with advanced follicular lymphoma
In a nutshell This study investigated the frequency of lymphoma transformation in patients with advanced-stage follicular lymphoma (FL) after treatment with BR (bendamustine, rituximab). This study concluded these patients might be at risk for lymphoma transformation after initial treatment. Some background FL is the second most common type of...
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