In a nutshell This study compared the safety of two different doses of nivolumab (Opdivo) plus ipilimumab (Yervoy) for patients with advanced melanoma. This study concluded that patients treated with nivolumab at 3mg/kg and ipilimumab at 1mg/kg had fewer side effects. Some background Advanced melanoma can be difficult to treat....
Read More
In a nutshell This study examined if vascular-targeted photodynamic therapy (VTPT), or active surveillance is more effective in the treatment of low-risk prostate cancer. This study concluded that patients who received VTPT were less likely to require radical therapy compared to those who underwent active surveillance. Some background...
Read More
In a nutshell This study examined the safety and effectiveness of slow-release leuprolide mesylate (LM) administered by injection under the skin (leuprolide mesylate subcutaneous injectable suspension or LMIS), in the treatment of advanced prostate cancer. This study concluded that this medication is safe and effective in the treatment of advanced...
Read More
In a nutshell This study determined whether osimertinib (Tagrisso) was more effective than erlotinib (Tarceva) in patients with non-small cell lung cancer (NSCLC) with the EGFR mutation. The study found that treatment with osimertinib improved survival compared to standard-care treatment for these patients. Some background...
Read More
In a nutshell This phase 2 trial will investigate the safety and effectiveness of a new targeted therapy drug, INCMGA00012 in metastatic (spread to other organs) non-small cell lung cancer (NSCLC). The main outcome will be the overall response rate. This trial is recruiting in Texas, United States. The details NSCLC is the most common form of...
Read MoreIn a nutshell This study compared the survival outcomes of patients with rectal cancer who underwent short- or long-course radiation therapy (RT). Researchers suggested that long-course RT was associated with greater tumor response and survival. Some background Colorectal cancer is the third most common cancer diagnosed in the United States. The...
Read More
In a nutshell This study investigated the effectiveness of prostate radiotherapy (RT) in prostate cancer (PC). They found that prostate RT may improve survival in men with PC and fewer than 5 bone metastasis (cancer that has spread to the bones). Some background Prostate cancer (PC) is a common and treatable cancer in men. One common type...
Read More
In a nutshell This phase 3 trial will investigate the effectiveness of pembrolizumab (Keytruda) in combination with pre-surgery chemotherapy and after-surgery hormonal therapy in patients with high-risk early-stage breast cancer (BC). The main outcomes to be measured will be the response to treatment and survival. The details...
Read MoreIn a nutshell This phase 3 trial will investigate the effectiveness of a new drug, DS-8201a, in the treatment of unresectable/metastatic breast cancer (UMBC). The main outcome will be survival without cancer worsening. The details Breast cancer (BC) originates from tissue in the breast. BC is treated with surgery to remove the cancer or...
Read MoreIn a nutshell This trial aims to find out if targeted radiotherapy on the breast in women with low-risk breast cancer after breast-conserving surgery will prevent the cancer from coming back. The main outcome that will be measured is how long it takes before the breast cancer comes back. The study is being conducted in Canada and the United States. The...
Read More
In a nutshell This study examined if single fraction, high dose brachytherapy for low and medium risk prostate cancer is safe and effective. This study concluded that this treatment for prostate cancer is safe and effective, however, it should not be used outside of clinical trials. Some background Prostate cancer can be treated using...
Read More
In a nutshell This study investigated the effect of X-ray brachytherapy (XRB) in the treatment of patients with rectal cancer who underwent local surgery. Researchers suggested that XRB is associated with improved outcomes and could be used instead of radical surgery. Some background Screening programs increased the number of patients being diagnosed...
Read More
