In a nutshell This review evaluated the safety and efficacy of focal salvage ablative therapy for the treatment of patients with prostate cancer recurrence (return of the cancer) after radiation therapy. Some background Radiation therapy (RT) is often used to treat early stage prostate cancer. However, after RT, the cancer may recur, locally...
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In a nutshell This review investigated treatment options following biochemical recurrence after primary treatment for prostate cancer. Some background Prostate cancer can be treated using a variety of methods, the most common being partial or full removal of the prostate gland, a procedure known as a prostatectomy. Other treatments include...
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In a nutshell This study examined the predictors of survival in prostate cancer that has spread to the lymph nodes. Some background Prostate cancer (PC) is being diagnosed at earlier stages due to modern screening techniques, particularly the prostate-specific antigen (PSA) testing (an enzyme in the blood that is elevated in PC patients). Despite...
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In a nutshell This study performed a 30-year analysis on the outcome of patients diagnosed with node-positive prostate cancer (N1PC) and treated by radical prostatectomy. Some background Radical prostatectomy is the surgical removal of the prostate gland, and is a common treatment for prostate cancer. During surgery, the surrounding lymph nodes...
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In a nutshell This study evaluated the outcomes of prostate cancer patients in terms of bladder control (continence), sexual function (potency) and cure rates after robot-assisted laparoscopic radical prostatectomy (RALRP). Some background RALRP is a modern technique which aims to completely remove the prostate gland and some healthy tissue around...
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In a nutshell This study evaluated the use of alendronate (Fosamax) for the prevention of bone loss in men undergoing androgen deprivation therapy (ADT) for localized prostate cancer. Some background Androgens are a group of hormones (including testosterone) which can stimulate the growth and spread of prostate cancer cells. Androgen deprivation...
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In a nutshell This article looked at the risk of adverse events such as heart disease, blood clots, strokes and fractures in patients diagnosed with prostate cancer. Some background Treatments for prostate cancer can result in numerous side effects. For example, endocrine (hormonal) treatments can result in low bone density (weak bones prone to...
Read MoreIn a nutshell This article looked at the effects of radiation therapy on bowel and urinary function in patients with prostate cancer. Three different methods of radiation therapy were compared:intensity-modulated radiotherapy (IMRT), proton beam therapy (PBT) and 3-dimensional conformal radiation therapy (3DCRT). Some background Radiation therapy...
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This review article describes clinical evidence of the benefits and risks of a treatment combined of a short course of hormonal therapy (termed ‘androgen deprivation therapy’, ADT) and radiation given in escalated doses. Patients involved were those with localized prostate cancer but higher Gleason score or prostate-specific antigen (PSA)...
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