In a nutshell This study aimed to investigate if MRI scans (a test that takes detailed images of inside the body) could safely replace biopsies (samples taken from tissues for close examination) in active surveillance for prostate cancer. This study found that men with low-risk disease can be monitored using MRI and PSA levels with selective...
Read MoreIn a nutshell This study aimed to determine whether differences in side effects reported over time in patients who had surgery or radiotherapy varied by risk group. This study found that for men with low-risk prostate cancer, radiotherapy was associated with higher sexual function scores at 3 years than surgery;...
Read MoreIn a nutshell This study aimed to evaluate two different timelines of delivering radiotherapy, 56 Gy delivered in 16 treatments or 67 Gy delivered in 25 treatments, to the prostate. This study found that both treatments are safe and effective in the treatment of prostate cancer. Some background Hypo-fractionated radiation therapy...
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In a nutshell This study aimed to examine the links between prostate specific antigen (PSA, a protein present in prostate cancer) and survival in patients with metastatic castration-resistant prostate cancer treated with cabazitaxel. This studty concluded that PSA response after cabazitaxel treatment is associated with improved...
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In a nutshell The authors aimed to determine patient outcomes following partial gland ablation compared to robot-assisted radical prostate surgery in men with low- and intermediate- risk prostate cancer. The authors concluded that men with cancer confined to the prostate benefited from partial gland ablation, as it was more successful with fewer side...
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In a nutshell This study investigated the impact monitoring an early stage prostate cancer had on quality of life or psychological state of mind. The study found that active surveillance or watchful waiting, instead of active treatment, has a minor impact on psychological and quality of life outcomes in the long-term. Some background Active...
Read MoreIn a nutshell The authors aimed to determine the effects of yoga on fatigue, erectile dysfunction, urinary problems and quality of life (QoL) in men undergoing radiation therapy for prostate cancer. The authors concluded that yoga twice-weekly during external beam radiation therapy (EBRT) significantly reduced pre-existing and radiation-related...
Read MoreIn a nutshell The authors aimed to determine the efficacy and safety of hypofractionated radiation therapy compared to conventional radiation therapy in men with localised prostate cancer. The authors concluded that hypofractionated therapy was beneficial to men with localised prostate cancer, without enhancing side effects, in comparison to...
Read MoreIn a nutshell The authors aimed to determine whether multiparametric magnetic resonance imaging (mpMRI)/ultrasound fusion biopsy improves Gleason grade detection compared to systematic biopsy in active surveillance. The authors concluded that due to the low sensitivity of mpMRI for detecting cancer grade 7 or higher, systematic biopsy will still need...
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In a nutshell The aim of this trial was to determine the difference in quality of life on urination when treated with low dose rate (LDR) and high dose rate (HDR) brachytherapy. This study is being conducted in Kelowna, British Columbia, Canada. The details Brachytherapy is a form of radiation therapy that places radioactive material either within...
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In a nutshell The authors aimed to determine the influence of biopsy timing on prostate cancer reclassification during active surveillance. The authors concluded that the timing of the first biopsy was not related to an increased risk of cancer reclassification, but prostate specific antigen (PSA) and body mass index (BMI – measured based...
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In a nutshell The authors aimed to determine how pre-operative blood fat levels affect the outcome in men with localized prostate cancer undergoing prostate surgery. The authors conclude that blood fats can cause adverse effects and act as an independent outcome predictor in men with prostate cancer following surgery. Some background...
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