In a nutshell This study aimed to evaluate laparoscopically harvested omental flap (LHOF) as used in breast reconstruction. It concluded that LHOF is a promising option in partial breast reconstruction after breast conserving surgery. Some background There are several types of surgery used in the treatment of breast cancer....
Read MoreIn a nutshell This trial is examining the effectiveness of a probiotic (Primal Defense Ultra (R) Probiotic Formula) for the immune systems of patients with breast cancer. The main outcome to be measured is the number of cytotoxic T lymphocytes (CD8+), a type of white blood cell. This study is being conducted in the Mayo Clinic in...
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In a nutshell This study examined whether radiotherapy treatment before surgery could improve disease-free survival, especially for patients with estrogen-receptor positive (ER+) breast cancer (dependent on the hormone estrogen for growth). This study concluded that radiotherapy before surgery improved disease-free survival. Some background For...
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In a nutshell This study investigated whether accelerated partial-breast irradiation (APBI) was useful for preoperative treatment of early-stage breast cancer (BC) patients. APBI was found to be an effective treatment option with good cosmetic results for certain early-stage BC patients. Some background Breast conserving therapy (surgery to remove...
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In a nutshell This study investigated whether exercise was associated with a reduction in the risk of cardiovascular disease (CVD) in patients with non-metastatic breast cancer (BC). Exercise was found to be linked to a significant reduction in the risk of CVD for this patient group. Some background CVD is a leading cause of death among women with...
Read MoreIn a nutshell This study investigated the long term risk of axillary (underarm lymph node) recurrence in breast cancer (BC) patients who were not treated with axillary lymph node dissection (ALND) following a negative sentinel node biopsy (SNB) result. The study concluded that the risk of axillary recurrence after 10 years was lower than expected after...
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In a nutshell This study investigated the rate of loco-regional recurrence (LRR) when breast-conserving surgery (BSC) was not followed by radiotherapy. This study concluded that the rate of LRR was low in patients who did not undergo radiation after BCS, but that age and margin width were risk factors for LRR. Some background BCS is a surgery...
Read MoreIn a nutshell This study investigated the complications that occur after intraoperative radiation therapy (IORT) treatment. The authors concluded that IORT is generally a safe treatment to use with BCS. Some background Breast-conserving surgery (BCS) treats breast cancer by removing just the tumor from the affected breast. IORT is sometimes...
Read MoreIn a nutshell This review outlined the recommended treatment options for invasive breast cancer. Some background Breast cancer is the most commonly diagnosed cancer in the world and it is the leading cause of cancer-related death in women. Breast cancer often begins in the milk ducts and lobules. In invasive breast cancer, the cancer moves...
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In a nutshell The authors aimed to determine whether long-term adjuvant (treatment given after the primary treatment) tamoxifen (Nolvadex) can reduce the risk of death by cancer in pre-menopausal women with estrogen-receptor positive (ER+) breast cancer. Long-term adjuvant tamoxifen treatment showed a reduction in the risk of death due to breast...
Read MoreIn a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...
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In a nutshell This study looked at the risk of developing contralateral breast cancer (CBC) in patients with or without BRCA mutations. The study concluded that age at the time of first cancer diagnosis is a strong risk factor for CBC in patients with BRCA. Some background Contralateral breast cancer (CBC) is the development of a second new breast...
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