In a nutshell This study investigated the effectiveness of mirabegron (Myrbetriq) on overactive bladder (OAB) in patients with benign prostatic hyperplasia (BPH) receiving tamsulosin (Flomax) therapy. Researchers suggested that mirabegron is a good and safe treatment for these patients. Some background OAB is present in 23% of the US population and...
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In a nutshell This study looked at the effect of nano-curcumin supplements on depression and anxiety in patients with diabetes and nerve damage. It found that taking nano-curcumin for eight weeks reduced depression and anxiety in these patients. Some background Patients with diabetes often have high rates of anxiety, depression, and stress. Poor...
Read MoreIn a nutshell This study investigated the effectiveness and safety of tadalafil (Cialis) plus mirabegron (Myrbetriq) in the treatment of overactive bladder (OAB). Researchers suggested that this combined treatment improves symptoms caused by OAB. Some background OAB consists of a frequent feeling of needing to urinate. It negatively impacts the...
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In a nutshell This study compared two different types of chemotherapy for patients with metastatic (spread to other parts of the body) colorectal cancer (mCRC). Researchers suggested that FOLFOXIRI plus bevacizumab (Avastin) is associated with better outcomes in these patients. Some background Colorectal cancer is the third most common cancer...
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In a nutshell This study looked at the side effects of dapagliflozin (Farxiga) for patients with type 2 diabetes (T2D). It found that dapagliflozin was well tolerated and led to less kidney injury for patients with T2D. Some background T2D is a disorder that causes high levels of glucose (sugar) in the blood. Over time, high blood glucose can cause a...
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In a nutshell This study examined the effectiveness and safety of the chemotherapy combination BV-DHAP for patients with relapsed or refractory Hodgkin lymphoma (HL). The authors found that BV-DHAP was an effective and safe treatment to progress patients to high-dose chemotherapy and stem cell transplant. Some background During treatment, some...
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In a nutshell This article reviewed biological therapies for patients with melanoma based on which type of disease they have. Some background Patients with melanoma are often treated with surgery to remove tumors first. In some cases, this is not enough. In other cases, patients have inoperable tumors. These patients are offered...
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In a nutshell This study set out to compare conventional-dose chemoradiotherapy (CRT) to reduced CRT based on 18F-FDG PET in locally advanced non-small cell lung cancer (NSCLC). The investigators found that 18F-FDG PET-based CRT improved tumor control without increasing side effects in these patients. Some background NSCLC accounts for...
Read MoreIn a nutshell This study aimed to investigate the influence of stomach acid suppressants on dasatinib treatment in patients with chronic-phase chronic myeloid leukemia. This study concluded that these drugs did not influence dasatinib treatment in this patient group. Some background...
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In a nutshell The study evaluated the effectiveness and safety of imatinib (Gleevec) in treating children and adolescents with chronic myeloid leukemia (CML). The main finding was that imatinib was effective against CML and safe in this patient population. Some background Imatinib deactivates a cancerous enzyme called BCR-ABL1. Lately, imatinib...
Read MoreIn a nutshell This review summarized recent changes in treatments of patients with chronic myeloid leukemia (CML). Some background Patients with CML carry a cancerous tyrosine kinase (TK) enzyme called BCR-ABL1. Traditionally CML had been treated by non-specific drugs with side effects. Stem cell transplants are alternatives but not...
Read MoreIn a nutshell This review compared initial treatments for patients with multiple myeloma (MM) that cannot be treated with a transplant. This study found that drug regimens which included the targeted treatments bortezomib or daratumumab had better outcomes. Some background MM is a cancer involving abnormal white blood cells called myeloma cells....
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