In a nutshell This study compared the effectiveness and safety of ABVD and BEACOPP chemotherapy for patients with advanced Hodgkin lymphoma (HL). The authors found that while BEACOPP was more effective in the short term, ABVD was as effective in the long term and safer for patients. Some background Chemotherapy is the standard initial treatment...
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In a nutshell This study examined if the addition of bortezomib (Velcade) to treatment with lenalidomide (Revlimid) and dexamethasone (Decadron) could improve treatment results long-term for patients with multiple myeloma (MM). The authors found that patients who received bortezomib had a longer survival long-term. Some background...
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In a nutshell This study investigated the effect of atezolizumab (Tecentriq) with chemotherapy before surgery in non-small cell lung cancer (NSCLC). They found that this treatment before surgery was safe and effective. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung cancer (LC)....
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In a nutshell This study examined if biological therapies nivolumab (Opdivo) and ipilimumab (Yervoy) could safely prevent cancer return in patients with stage IV melanoma that has been surgically removed. The results showed that nivolumab and ipilimumab were effective at preventing recurrence but nivolumab alone was safer for patients. Some...
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In a nutshell This study reviewed the effectiveness and safety of phosphodiesterase type 5 inhibitors (PD5I) to treat men with erectile dysfunction. Researchers suggested that PD5I therapy improves the treatment outcomes of these patients. Some background Erectile dysfunction affects around 50% of men between 40 and 70 years. It...
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In a nutshell This study investigated the feasibility and adherence of a combined training treatment for stroke survivors. Researchers suggested that this treatment is safe and has significant adherence from patients. Some background A stroke happens when the blood flow to the brain is blocked. Brain cells stop receiving oxygen and begin to die. These...
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In a nutshell This study aimed to investigate if arsenic trioxide was safe and effective as a maintenance treatment for patients with acute promyelocytic leukemia. This study concluded that this maintenance treatment was safe and effective in these patients. Some background Acute promyelocytic...
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In a nutshell This study compared human menopausal gonadotropin (hMG) to follicle-stimulating hormone (FSH) prior to intracytoplasmic sperm injection (ICSI) for patients predicted to have a strong ovarian response. It found that both types of gonadotropin hormone were effective, but that hMG had fewer side effects and miscarriages. Some background...
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In a nutshell This study compared traditional in vitro fertilization (IVF) to intracytoplasmic sperm injection (ICSI) for in vitro maturation of eggs. It found that both insemination methods led to good fertilization and pregnancy outcomes for patients with polycystic ovarian syndrome (PCOS). Some background PCOS is a condition in which a woman has...
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In a nutshell This study compared local cryosurgery (CRYO) against androgen deprivation therapy (ADT) for the treatment of locally recurring prostate cancer (LRPC). The study found local cryosurgery had a longer overall survival (OS) when compared to ADT. Some background LRPC is cancer that has re-occurred in the prostate gland...
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In a nutshell This study aimed to investigate the safety and effectiveness of zanubrutinib in patients with relapsed/unresponsive chronic lymphocytic leukemia. This study concluded that zanubrutinib was well tolerated and with promising effectiveness in these patients. Some background Bruton...
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In a nutshell This study aimed to investigate the safety and effectiveness of zanubrutinib in patients with relapsed/unresponsive chronic lymphocytic leukemia and small lymphocytic lymphoma. This study concluded that zanubrutinib was well tolerated and with promising effectiveness in these patients. Some background Bruton tyrosine...
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