In a nutshell This study examined how effective S-1 (Teysuno) chemotherapy is for patients with advanced non-small cell lung cancer (NSCLC) following initial chemotherapy treatment. The results showed that S-1 improved patients’ survival without NSCLC worsening but increased the number of side effects. Some background Treatment for patients...
Read MoreS1-based chemotherapy improves the outcomes of patients with advanced colorectal cancer
In a nutshell This study compared the effectiveness and safety of two different chemotherapies in the treatment of advanced colorectal cancer (CRC). Researchers suggested that S1-based chemotherapy is a good option for the treatment of these patients. Some background CRC is one of the most common cancers worldwide. The standard treatment is surgery...
Read MoreEvaluating the risk of secondary cancers after internal radiation therapy in patients with prostate cancer
In a nutshell This study looked at the long-term risk of secondary cancers following brachytherapy (BT; internal radiation therapy) for prostate cancer. It found that treating prostate cancer with BT had a low risk of secondary cancers. Some background Prostate cancer is a slow-growing cancer of the prostate gland. Men with prostate cancer that has...
Read MoreHow safe and effective is biological therapy ranibizumab for patients with diabetic macular edema?
In a nutshell This study examined the effectiveness and safety of biological therapy ranibizumab (Lucentis) for patients with diabetic macular edema (DME) that has never been treated. After one year, patients’ vision had improved significantly, particularly for patients who received 5 injections instead of 4. Some background Diabetic...
Read MoreCytarabine, aclarubicin and G-CSF as salvage treatment for hard to treat T cell acute lymphoblastic leukemia
In a nutshell This study aimed to investigate cytarabine (Cytosar-U), aclarubicin (Aclacin) and G-CSF (Neupogen) as a salvage treatment for adult patients with relapsed or refractory T cell acute lymphoblastic leukemia. This study concluded that this treatment combination is safe and effective as a salvage treatment...
Read MoreWhat is the best treatment approach for patients newly diagnosed with multiple myeloma?
In a nutshell This study investigated which was the best treatment approach before and after stem cell transplantation (SCT) for patients newly diagnosed with multiple myeloma (MM). The results showed that patients’ survival was better with CRD (cyclophosphamide, lenalidomide, and dexamethasone) chemotherapy than with CTD (cyclophosphamide,...
Read MoreCan an intensive lifestyle change reduce diabetes symptoms in patients with early type 2 diabetes?
In a nutshell This study examined if an intensive diet and exercise plan could reduce blood glucose levels and body weight of patients with early type 2 diabetes (T2D). The results showed that an intensive lifestyle change significantly reduced the number of patients with T2D and patients’ body weight. Some background The high blood...
Read MoreIs an anti-clotting injection selatogrel effective for patients suffering from heart attacks?
In a nutshell This study examined how fast and effective a dose of an anti-clotting injection, selatogrel, was for patients suffering from heart attacks. The authors found that both doses were effective by 30 minutes, but the high dose worked faster. Some background At the beginning of a heart attack, patients should be given anti-clotting...
Read MoreCan oral relugolix be used as androgen-deprivation therapy in advanced prostate cancer?
In a nutshell The study looked at whether oral relugolix (Orgovyx, Relumina) could be used to suppress testosterone in men with advanced prostate cancer compared to leuprolide (Lupron). This study showed that relugolix was associated with more rapid and effective suppression of testosterone levels when compared...
Read MoreDoes enzalutmide improve survival in nonmetastatic, castration-resistant prostate cancer?
In a nutshell The study assessed whether enzalutamide (Xtandi) plus androgen deprivation therapy (ADT) increased overall survival (OS) of patients with nonmetastatic, castration-resistant prostate cancer (CRPC). The study found improved survival in patients with CRPC treated with enzalutamide. Some background ADT is a type of hormonal therapy...
Read MoreBladder training improves the outcomes of patients with Parkinson’s disease and urinary symptoms
In a nutshell This study investigated the effectiveness of bladder training in patients with Parkinson's disease (PD) and urinary symptoms (US). Researchers suggested that BT improves the outcomes of these patients. Some background Parkinson's disease (PD) is a chronic disorder that affects brain cells. These cells lose their ability to...
Read MoreAcalabrutinib in patients with relapsed or refractory chronic lymphocytic leukemia
In a nutshell This study aimed to investigate if acalabrutinib (Calquence) was safe and effective as a treatment for patients with relapsed or refractory chronic lymphocytic leukemia. This study concluded that acalabrutinib was safe and effective in these patients. Some background Acalabrutinib is commonly...
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