In a nutshell This initial study looked at using CAR T cells with two targets to treat relapsed B cell non-Hodgkin lymphoma (NHL). It found that this type of immunotherapy was safe and effective, and may cause less inflammation than other types of CAR T cell treatment. Some background Chimeric antigen receptor T (CAR T) cells are a treatment for...
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In a nutshell This study investigated if intralipid (IL) improves pregnancy outcomes after previous implantation failure (IF). They found that IL may improve pregnancy outcomes in these women. Some background Infertility is becoming increasingly common. Assisted reproduction (AR) is used to treat infertility. In vitro...
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The protrusions on the Coronavirus are a group of three “S” proteins also call “Spike” proteins. These proteins bind to ACE2 receptors on the membranes of cells in the body. This has been a target of many of the over 120 vaccines that have been in production since the pandemic began. A recent intermediary report on one of the...
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In a nutshell This study evaluated whether the safety and effectiveness of iodine (I)-seeded brachytherapy (IBT) for the treatment of NSCLC in older people. The study found that CT-guided IBT is an effective and safe therapy and can be considered as an alternative to surgery and radiotherapy for elderly patients with NSCLC. Some background...
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In a nutshell This study investigated the effectiveness of panitumumab (Vectibix) and capecitabine (Xeloda) combination to treat older patients with advanced colorectal cancer (CRC). Researchers suggested that this combination is a good and safe treatment for older patients with CRC. Some background CRC is a common cancer worldwide. CRC patients are...
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In a nutshell This study looked at the effect of pembrolizumab (Keytruda) to treat classical Hodgkin lymphoma (cHL) which had relapsed after previous treatments including brentuximab vedotin (Adcetris). It found that pembrolizumab was effective for these patients. Some background cHL is typically treated with chemotherapy, and sometimes with radiation...
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In a nutshell This study looked at the targeted therapy nivolumab (Opdivo) to treat relapsed classical Hodgkin lymphoma (cHL). It found that most patients with relapsed cHL responded to nivolumab. Some background HL is a cancer of the lymph nodes which has good treatment options. However, roughly a third of patients with cHL will have the cancer...
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In a nutshell This study investigated the effectiveness of bulk injection therapy with polydimethylsiloxane Urolastic (PDSU; Urogyn) in the treatment of stress urinary incontinence (SUI). Researchers suggested that some patients treated with PDSU were cured 2 years after treatment. Some background Urinary incontinence (UI) consists of leakage of...
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In a nutshell This study investigated the impact of trimetazidine (Vastarel MR) in the treatment of patients with Parkinson's disease (PD). Researchers suggested that the use of trimetazidine should be avoided in PD. Some background PD is one of the most common brain diseases. It affects brain cells which are responsible for several body...
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In a nutshell The aim of this study was to evaluate the safety and effectiveness of combining androgen deprivation therapy (ADT) with docetaxel (Taxotere) plus prednisone (Deltasone) in the treatment of metastatic hormone-sensitive prostate cancer (mHSPC). The study found that this combination improved the outcomes of these...
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In a nutshell The study evaluated the effects of trastuzumab emtansine (T-DM1; Kadcyla) to treat patients with brain metastasis (BM) from HER2-positive metastatic breast cancer (mBC). The main finding was that T-DM1 was safe and effective in such patients. Some background HER-2 positive mBC cells have an excess of the HER-2 protein. Such cancers...
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In a nutshell This study evaluated the long-term outcomes of patients with ALK-positive non-small-cell lung cancer (NSCLC) treated with alectinib (Alecensa). This study concluded that this treatment improved survival without cancer worsening in these patients. Some background ALK-positive non-small-cell lung cancer (NSCLC) remains a difficult to treat...
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