In a nutshell This article looked at different types of non-drug therapies for the management of menopausal symptoms (MS) such as night sweats and hot flushes in breast cancer (BC) survivors. The authors concluded that cognitive-behavioral therapy (CBT) and hypnosis may offer some benefit for these women. Some background BC is the most common cancer...
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In a nutshell This trial was carried out to examine the effectiveness and safety of selpercatinib (Retevmo) in treating RET-positive non-small-cell lung cancer (NSCLC). The authors concluded that selpercatinib had good effectiveness and low toxicity in these patients. Some background NSCLC is responsible for 85% of all lung cancer...
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In a nutshell The study evaluated outcomes of lapatinib (Tykerb), trastuzumab (Herceptin), and aromatase inhibitor (AI) in postmenopausal women with human epidermal growth factor receptor 2-positive (HER2+) and hormone receptor-positive (HR+) metastatic breast cancer (MBC). The authors found that the combination was safe and effective in such...
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In a nutshell The purpose of this study was to assess the dose of radiation delivered to organs at risk with modern radiotherapy (RT) in patients with early-stage Hodgkin lymphoma (HL). The authors found that 2 cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) and 20Gy of RT for early-stage HL was highly effective...
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In a nutshell This trial was carried out to assess the effectiveness and safety of veliparib (ABT-888) in combination with carboplatin (Paraplatin) and paclitaxel (Taxol) in BRCA-mutated advanced breast cancer (BC). The authors found that the addition of veliparib to platinum-based chemotherapy resulted...
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In a nutshell This study compared the effectiveness and safety of pitavastatin (Livalo) alone to combination therapy with fenofibrate (Tricor) for patients with dyslipidemia (high blood fats). The study showed that combination therapy was more effective in lowering the levels of harmful fats in the blood. Some background...
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In a nutshell This study investigated the effect of different kinds of lifestyle changes in patients with high blood pressure (BP) in the beginning stages (prehypertension) and full-blown hypertension. They found that a life-long change in eating called Dietary Approach to Stop Hypertension (DASH) has the most positive...
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In a nutshell This study looked at the use of mirogabalin (Tarlige) to treat diabetic peripheral neuropathic pain (DPNP). It found that mirogabalin was safe and effective at reducing pain in DPNP. Some background Diabetic peripheral neuropathic pain (DPNP) is a pain experienced by some diabetic patients due to nerve damage. This pain,...
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In a nutshell This study looked at the benefit of injecting a steroid pellet into the eye during cataract surgery in patients with diabetic eye disease. They found that steroid injections reduced the risk of complications in patients with diabetic eye disease. Some background Patients with diabetes often suffer from fluid in the...
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In a nutshell This study aimed to investigate the safety and effectiveness of C-CAG including cladribine (Leustatin), granulocyte colony-stimulating factor (G-CSF, Neupogen), cytarabine (Cytosar-U), and aclarubicin (Aclacinon) in patients with relapsed/refractory (r/r) acute myeloid leukemia (AML). This study...
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In a nutshell This study aimed to investigate three different chemotherapy-free treatment regimens for patients with chronic lymphocytic leukemia. This study concluded that acalabrutinib (Calquence) plus obinutuzumab (Gazyva) improved survival without cancer worsening for these patients. Some background Chemotherapy-free...
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In a nutshell This study investigated the association between levodopa treatment and time to dyskinesia (DYS) development in patients with Parkinson’s disease (PD). Researchers suggested that a quick increase in levodopa dose is associated with early DYS. Some background PD is a chronic disorder that affects the brain cells. Body...
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