In a nutshell This study looked at tirzepatide, a new treatment for type 2 diabetes, compared to semaglutide (Ozempic). It found that, depending on the dose, tirzepatide was similarly or more effective at controlling blood glucose than semaglutide. Some background Tirzepatide is a new type of medication designed to treat type 2...
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In a nutshell This study compared the effectiveness and safety outcomes of atezolizumab (Tecentriq) alone or with chemotherapy (CT) for the treatment of patients with advanced non-small-cell lung cancer (NSCLC). The data showed that atezolizumab alone might be a better treatment option than atezolizumab plus CT for these patients. Some...
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In a nutshell This trial aims to assess the safety and effectiveness of an experimental drug, CYT-0851 in the treatment of B-cell and solid tumors, including small cell lung cancer, that have come back or are no longer responsive to treatments. The main outcomes to be measured are the side effects and the overall response to the treatment. This trial is...
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In a nutshell This trial aims to assess the safety and effectiveness of an experimental drug, CYT-0851 in the treatment of B-cell and solid tumors, including multiple myeloma (MM), that have come back or are no longer responsive to treatments. The main outcomes to be measured are the side effects and the overall response to the treatment. This trial is...
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In a nutshell This trial aims to assess the safety and effectiveness of an experimental drug, CYT-0851 in the treatment of B-cell and solid tumors, including non-Hodgkin lymphoma (NHL), that have come back or are no longer responsive to treatments. The main outcomes to be measured are the side effects and the overall response to the treatment. This trial...
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In a nutshell This trial aims to assess the safety and effectiveness of an experimental drug, CYT-0851 in the treatment of B-cell and solid tumors, including chronic lymphocytic leukemia (CLL), that have come back or are no longer responsive to treatments. The main outcomes to be measured are the side effects and the overall response to the treatment....
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In a nutshell This trial aims to assess the safety and effectiveness of an experimental drug, CYT-0851 in the treatment of B-cell and solid tumors, including breast cancer, that have come back or are no longer responsive to treatments. The main outcomes to be measured are the side effects and the overall response to the treatment....
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In a nutshell This article compared the safety and effectiveness of PD-L1/PD-1 immunotherapies (IT) for non-small cell lung cancer (NSCLC). The authors found that in the first-line setting, the most effective treatments for PD-L1 positive NSCLC were atezolizumab (Tecentriq), pembrolizumab (Keytruda)/chemotherapy (CT) combination, and nivolumab...
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In a nutshell This study investigated the safety and effectiveness of afatinib (Gilotrif) in patients with non-small cell lung cancer (NSCLC) who have not previously received EGFR tyrosine kinase inhibitors (TKIs). Data showed that afatinib was well tolerated and improved the outcomes of these patients. Some background NSCLC...
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In a nutshell This study examined the use of paclitaxel (Taxol) and carboplatin (Paraplatin) as weekly chemotherapy (CT) with trastuzumab (Herceptin) and pertuzumab (Perjeta) in HER2+ breast cancer (BC) in order to reduce toxicity rates. The authors found that the weekly regimen of chemotherapy can be considered an alternative to standard chemotherapy...
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In a nutshell This trial looked at the long-term effectiveness and safety of ixazomib (Ixa; Ninlaro) in combination with lenalidomide (R; Revlimid), and dexamethasone (d; Decadron) for the treatment of relapsed/refractory (RR) multiple myeloma (MM). The authors found that there was an improved survival with Ixa-Rd...
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In a nutshell This study looked at the use of olaparib (Lynparza) treatment for patients with high risk, BRCA1/2-positive, HER2-negative breast cancer (BC). The authors found that in patients with BRCA1/2-positive BC, olaparib after local treatment improved the outcomes of these patients. Some background BC is one of the most common cancers...
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