In a nutshell This study evaluated the effectiveness of brentuximab vedotin (Adcetris) plus bendamustine (Treanda) for patients with hard to treat classical Hodgkin lymphoma (cHL). This study found that this regimen is an effective salvage therapy for these patients. Some background Standard first-line chemotherapy is highly effective in treating...
Read MoreShould children with ALL be revaccinated after chemotherapy?
In a nutshell This study evaluated the outcomes of vaccination in children with acute lymphoblastic leukemia (ALL). This study found that children had less vaccine protection after chemotherapy. Some background Vaccines help the immune system recognize a pathogen using dead or weakened bacteria or viruses. Vaccines are not effective if someone’s...
Read MoreCan dasatinab improve outcomes for patients with acute myeloid leukemia?
In a nutshell This study looked at combining chemotherapy with dasatinib (Sprycel) to treat patients with acute myeloid leukemia (AML) with a CBF mutation. This study found that dasatinib was a safe and effective treatment for these patients. Some background AML is a cancer of immature blood cells called myeloid cells. Around 12% of AML cases...
Read MoreEvaluating the impact of lymphoma treatments on bone health
In a nutshell This study evaluated the impact of first-line lymphoma treatments including high-dose prednisolone (Deltasone) on bone health in patients with non-Hodgkin lymphoma (NHL). This study concluded that first-line lymphoma treatments increased the risk of osteoporosis in patients with lymphoma, especially for women and elderly...
Read MoreDoes omitting radiotherapy improve outcomes for patients with early-stage Hodgkin lymphoma?
In a nutshell This study evaluated the outcomes of removing radiotherapy from treatment for patients with early-stage Hodgkin lymphoma (HL). This study concluded that radiotherapy improved survival without disease progression for patients while omitting it did not affect overall survival. Some background Chemotherapy followed by radiotherapy (RT)...
Read MoreStem cell therapy is a safe treatment that improves the recovery of stroke survivors
In a nutshell This study investigated the safety and effectiveness of the human neural stem cell line (HNSCL) CTX0E03 in the treatment of stroke survivors. Researchers suggested that treatment with HNSCL improves the upper limb (arms) function in these patients. Some background Stroke is the second most common cause of death and the first cause of...
Read MoreEvaluating Glyxambi for patients with Type 2 diabetes
In a nutshell This study evaluated empagliflozin (Jardiance) and linagliptin (Tradjenta) for the treatment of Type 2 diabetes (T2D). This study found that combining both drugs (Glyxambi) was more effective at lowering blood glucose levels than either medication alone, with similar side effects. Some background For patients with T2D, the...
Read MoreZinc and Immunity: Just Don’t It Take With Citric Acid
You’ve probably seen the cold remedies and supplements that contain zinc and their promises of increased immunity against colds. Have you wondered if the marketing is true? Do Humans Need Zinc in Our Diet? In 1961, Dr. Anada Prasad and some colleagues wrote a case study for the American Journal of Medicine. Prasad had travelled to Iran for a research...
Read MoreCan a stem cell transplant improve outcomes of patients with cHL after nivolumab treatment?
In a nutshell This study evaluated the outcomes of a stem cell transplant after nivolumab (Opdivo) therapy in patients with classical Hodgkin’s lymphoma (cHL) that came back or stopped responding to treatment. This study concluded that nivolumab followed by stem cell transplant is safe and effective for these patients. Some background...
Read MoreBenefits of therapy for early stage breast cancer
In a nutshell This paper is a document that was developed at a breast cancer conference by a number of experts in the field. It outlines suggested treatment for early-stage breast cancer. The experts concluded that patients and doctors should work together and discuss the benefit of treating early-stage breast cancer in comparison with the potential...
Read MoreIntensity-modulated radiation therapy improves tumor response in anal cancer
In a nutshell This study investigated tumor response and safety of intensity-modulated radiation therapy (IMRT) in anal cancer. Researchers reported an excellent response result and low short-term side effects for IMRT in these patients. Some background Colorectal cancer is one of the most common cancers worldwide. Anal cancer is a rare form of CRC...
Read MoreVenetoclax in elderly patients with relapsed or unresponsive chronic lymphocytic leukemia
In a nutshell This study aimed to investigate if venetoclax was safe and effective in older patients with relapsed/refractory chronic lymphocytic leukemia outside of clinical trials. This study concluded that venetoclax is safe and effective in these patients. Some background Chronic lymphocytic leukemia (CLL) is commonly diagnosed in older people....
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