In a nutshell This study examined whether it is possible to predict side effects and prognosis following salvage cryotherapy in patients with prostate cancer. Some background Salvage therapy is a form of treatment given after a cancer does not respond or returns after a main treatment. More than 30% of prostate cancer patients develop a recurrence...
Read MoreReducing side effects of ixabepilone by reducing dosage
In a nutshell In this study researchers reviewed the adverse effects of the chemotherapy drug ixabepilone for patients with metastatic breast cancer and how these can be managed by reducing the dosage. Some background Ixabepilone (Ixempra) is a chemotherapy drug approved by the U.S. FDA as treatment for metastatic breast cancer (breast cancer that...
Read MoreAnastrozole and letrozole are associated with equal rates of side effects
In a nutshell Researchers compared therapy with anastrozole (arimidex) and letrozole (femara) to determine the effects of these drugs on the quality of life (QoL) of breast cancer patients. Some background In the case of hormone receptor positive (HR+) breast cancer, patients typically receive surgery, followed by adjuvant (additional) treatment...
Read MoreFocal Ultrasound-based therapy for prostate cancer as means to reduced genito-urinary side effects
In a nutshell This study evaluated whether focal Ultrasound-based therapy of individual cancer lesions can minimize the side effects associated with radical therapy that involves the whole prostate gland. Main findings: Focused therapy directed into cancer tissues significantly reduces genitourinary side effects like urine-leakage and impotence. Some...
Read MoreRadiation therapy for prostate cancer: how long do urinary-related side effects last?
In a nutshell The present study examined the duration of urinary-related side effects resulting from radiation therapy. Mild to severe urinary side effects were found to last up to 10 years post radiation therapy. Some background Prostate cancer is a slow growing form of cancer that is often managed by active surveillance or observation (delayed...
Read MoreThe effects of blinatumomab in patients with relapsed or unresponsive acute lymphoblastic leukemia in outside of clinical trials
In a nutshell The study evaluated the safety and effectiveness of blinatumomab (Blincyto) in patients with relapsed or unresponsive B-acute lymphoblastic leukemia (B-ALL) outside of clinical trials. The authors found that blinatumomab was safe and effective to treat such patients in real-world medical practice. Some background Relapsed...
Read MoreOutcomes and side-effects after prostate surgery and intensity modulated radiation therapy
In a nutshell This study aimed to investigate long-term outcomes of radiation therapy after prostate surgery for prostate cancer. This study found that this is a safe treatment option for these patients. Some background Prostate surgery is a common treatment for prostate cancer (PCa). Intensity-modulated radiation therapy (IMRT) is another option....
Read MoreManaging side-effects of collagenase Clostridium histolyticum injection
In a nutshell This study aimed to review side-effects for collagenase Clostridium histolyticum (CCH) treatment for Peyronie's disease (PD). This study found that common side-effects of CCH include pain, swelling and bleeding. Some background Peyronie's disease (PD) is caused by scar tissue that forms inside the penis. It can result...
Read MoreA review of the side-effects of Nivolumab (Opdivo) treatment for Hodgkin Lymphoma.
In a nutshell This paper summarised the side effects associated with the use of nivolumab (Opdivo) for the treatment of Hodgkin Lymphoma. The main finding was that patients treated with nivolumab may experience immune-related side effects. Some background Brentuximab vedotin (Adcetris) and stem cell transplant are often used to treat classical...
Read MoreSide-effects and quality of life changes after robotic prostate surgery
In a nutshell This study aimed to evaluate short and medium-term patient-reported side-effects after robotic prostate surgery. This study found that patient-reported outcome measures evaluating urinary symptoms and health related quality of life do not significantly change after robotic prostate surgery. Some background...
Read MoreDo side-effects vary between risk groups after treatment for localized prostate cancer?
In a nutshell This study aimed to determine whether differences in side effects reported over time in patients who had surgery or radiotherapy varied by risk group. This study found that for men with low-risk prostate cancer, radiotherapy was associated with higher sexual function scores at 3 years than surgery;...
Read MoreWhich method of insulin therapy is best for preventing side-effects in children and young people?
In a nutshell This study assessed the ability of two types of insulin therapy in preventing possible side effects of type 1 diabetes (T1D) in young patients. The authors concluded that insulin pump therapy was better than injection therapy at preventing hypoglycemia and diabetic ketoacidosis...
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