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Posted by on Jul 21, 2019 in Prostate cancer | 0 comments

In a nutshell

This study aimed to investigate long-term outcomes of radiation therapy after prostate surgery for prostate cancer. This study found that this is a safe treatment option for these patients.

Some background

Prostate surgery is a common treatment for prostate cancer (PCa). Intensity-modulated radiation therapy (IMRT) is another option. This type of radiation is very precise and is thought to lessen side-effects after treatment. IMRT after prostate surgery may reduce the risk of recurrence in high-risk patients. However, the safety of IMRT after prostate surgery remains under investigation.

Methods & findings

This study included 199 men with prostate cancer. All patients had prostate surgery followed by IMRT. 66% of the patients also had hormone therapy. They were followed up for 33 months. They completed questionnaires about their quality of life. 

4 years after treatment, 94% of men did not have any serious urinary side-effects (burning, bleeding). 95% of men did not experience bowel upset (diarrhea, pain). Risk factors for having more side-effects and a lower quality of life after treatment were noted. High body mass index, older age, smoking, and higher treatment doses were risk factors for a lower quality of life. 

The bottom line

This study found that surgery followed by IMRT is a safe treatment option for PCa. 

The fine print

Some patients were lost at follow-up. This might influence the results. Further studies are needed.

Published By :

European Urology

Date :

May 18, 2019

Original Title :

Patient-reported Outcomes and Late Toxicity After Postprostatectomy Intensity-modulated Radiation Therapy.

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