In a nutshell This study evaluated whether a modern treatment approach is suitable in patients with rheumatoid arthritis (RA) that were pregnant or intended to become pregnant. The authors concluded that low disease activity (LDA) and remission are possible with a modern approach in these women. Some background RA is an inflammatory disease....
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In a nutshell This study assessed the link between smoking and seropositivity levels of specific autoantibodies in patients with rheumatoid arthritis (RA). The authors concluded that patients with RA who were current smokers had significantly higher seropositivity levels than those that never smoked. Some background Smoking is an environmental risk...
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In a nutshell This study evaluated potential predictors of erosions and joint space narrowing (JSN) in patients with early rheumatoid arthritis (RA). The data showed that less JSN progression was seen in postmenopausal, overweight women with RA, and smoking was associated with JSN progression. Some background RA is an autoimmune disease that is...
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In a nutshell This study evaluated whether methotrexate use increased the presence of liver fibrosis (scarring) in patients with rheumatoid arthritis (RA). The data showed that there was no increase in the rate of liver fibrosis in patients with RA that received methotrexate. Some background RA is an inflammatory disease that affects the joints....
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In a nutshell This study investigated the possible effects of Punica granatum (pomegranate) on indicators and symptoms caused by rheumatoid arthritis (RA). The data showed that pomegranate may have a positive impact on RA-related indicators and symptoms. Some background The inflammation caused by RA can lead to symptoms like swollen...
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In a nutshell This study reviewed the effectiveness of baricitinib (Olumiant) on the progression of structural joint damage (SJD) in patients with rheumatoid arthritis (RA). The data showed that baricitinib may significantly help slow down SJD signs found in digital imaging in patients with non-existent or insufficient...
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In a nutshell This study examined the effect of sarilumab (Kevzara) compared to adalimumab (Humira) on health-related quality of life (HRQoL) based on inflammatory marker levels in patients with rheumatoid arthritis (RA). The data showed that sarilumab has a higher effect on improving aspects of HRQoL in patients...
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In a nutshell This study compared the effectiveness of tocilizumab (Actemra) alone (monotherapy) to combination therapy with tocilizumab and methotrexate (Trexall) in patients with rheumatoid arthritis (RA). The study concluded that combination treatment...
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In a nutshell This study investigated the relationship between the diagnosis of rheumatoid arthritis (RA) and the development of lung diseases (LDs) over five years. The study showed that the markers of RA activity were associated with the development of lung disease. Some background LDs such as interstitial lung disease...
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In a nutshell This trial was carried out to examine the effectiveness of switching from upadacitinib (UPA; Rinvoq) to adalimumab (ADA; Humira) and from ADA to UPA following insufficient response in patients with rheumatoid arthritis (RA). The authors found that patients who do not respond to UPA or ADA can be...
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In a nutshell This study investigated the effect of disease-modifying anti-rheumatic drugs (DMARDs) on cardiovascular disease (CVD) risk. They found that abatacept (Orencia) and tumor necrosis factor inhibitors (TNFi) were associated with decreased CVD risk. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by...
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In a nutshell This study reviewed infection risk in patients treated with biologic and targeted disease-modifying anti-rheumatic drugs (DMARDs) in patients with rheumatoid arthritis (RA). Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by painful inflammation in the joints. RA is treated with drugs to reduce...
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