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Rheumatoid Arthritis Posts on Medivizor

Predicting treatment success in early RA: can biomarkers predict methotrexate response?

Posted by on Feb 26, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated if biomarkers (BMs) can predict the response to methotrexate (MTX) in early rheumatoid arthritis (RA). They found that the level of BMs at baseline could predict the success of MTX treatment. Some background Rheumatoid arthritis (RA) is a condition caused by inflammation. This leads to painful swelling...

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Reducing cardiovascular disease risk in rheumatoid arthritis: is treat-to-target the best approach?

Posted by on Feb 26, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated if a treat-to-target (TTT) approach reduces cardiovascular disease (CVD) risk in patients with rheumatoid arthritis (RA). They found that TTT reduced CVD risk in patients with RA over 5 years.  Some background Rheumatoid arthritis (RA) is a chronic condition caused by inflammation. Patients with RA have...

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Seasonal effects in rheumatoid arthritis: when is disease activity lowest?

Posted by on Jan 31, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated disease activity in patients with rheumatoid arthritis (RA) by season. They found that disease activity was lowest in fall and highest in spring. Some background Rheumatoid arthritis (RA) is a condition affecting the joints of the body. In RA, there is an excess of inflammation. This leads to painful swelling...

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Looking for patients with rheumatoid arthritis to test a new drug

Posted by on Jan 27, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This phase 1b/2a trial will investigate the safety and effectiveness of AMG 592 in rheumatoid arthritis (RA). The main outcome will be a 20% improvement in symptoms at week 12.  The details Rheumatoid arthritis (RA) is a condition caused by long-term inflammation. This leads to painful swelling in the joints. To treat RA, drugs that...

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Is vitamin D deficiency linked to disease activity in juvenile idiopathic arthritis?

Posted by on Jan 20, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated if vitamin D levels and disease activity are linked in juvenile idiopathic arthritis (JIA). They found that low vitamin D levels were associated with higher disease activity. Some background Juvenile idiopathic arthritis (JIA) is caused by inflammation in the joints. The cause of JIA is unknown. In JIA, the...

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Searching for participants to trial a new ultrasound treatment for rheumatoid arthritis

Posted by on Jan 19, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This clinical study will investigate the use of daily ultrasound for the treatment of rheumatoid arthritis (RA).   The main outcome of interest is an improvement in RA disease activity. The trial will take place in Minneapolis, Minnesota, United States. The details Rheumatoid arthritis (RA) is a long-term condition caused...

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What is the best strategy to achieve remission in juvenile idiopathic arthritis?

Posted by on Jan 18, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated three treatment strategies to achieve remission in patients with juvenile idiopathic arthritis (JIA). They found that all treatment strategies were effective in achieving remission in JIA. Some background Juvenile idiopathic arthritis (JIA) is caused by inflammation. It causes painful swelling in the joints...

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Intensive treatment – is this the most effective approach to achieving remission in rheumatoid arthritis?

Posted by on Jan 18, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated intensive treatment to achieve remission in rheumatoid arthritis (RA). They found that intensive treatment was effective at achieving remission. Some background Rheumatoid arthritis (RA) is a long-term condition. It is caused by painful inflammation in the joints. To treat RA, patients are prescribed drugs...

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Is it possible to maintain low disease activity in rheumatoid arthritis with low dose baricitinib?

Posted by on Jan 10, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated if reducing the dose of baricitinib (BCB; Olumiant) maintained low disease activity (LDA) in rheumatoid arthritis (RA). They found that a lower dose of BCB maintained LDA in some patients while the others could be rescued by switching to the original dose.  Some background Rheumatoid...

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Tofacitinib for the treatment of rheumatoid arthritis: evidence from real-world clinical practice

Posted by on Dec 25, 2018 in Rheumatoid Arthritis | 0 comments

In a nutshell This study reviewed information on the use of tofacitinib (Xeljanz) for the treatment of rheumatoid arthritis (RA). They found that tofacitinib is effective and well-tolerated for patients with RA. Some background Tofacitinib (TFB) is a new drug to treat rheumatoid arthritis (RA). It blocks a type of enzyme...

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