In a nutshell This study investigated if patients with rheumatoid arthritis had an increased risk of serious infection when treated with denosumab (Xgeva) or biological DMARDs. They found that there was a low incidence of serious infection in patients taking denosumab and/or biological DMARDs. Some background Rheumatoid arthritis (RA) is a...
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In a nutshell This study investigated if remission had any impact on the risk of infection in patients with rheumatoid arthritis. They found that the incidence of serious infection was significantly lower in patients in remission from rheumatoid arthritis. Some background Rheumatoid arthritis (RA) is a chronic condition that is caused by the...
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In a nutshell This study investigated the safety and effectiveness of switching to SB2 from infliximab (Remicade) in patients with rheumatoid arthritis. They found that switching to SB2 from infliximab was well tolerated and effective at reducing disease activity. Some background Rheumatoid arthritis (RA) is a chronic disease that causes...
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In a nutshell This study investigated whether there is an increased risk of hospitalization for chronic obstructive pulmonary disorder in rheumatoid arthritis patients. They found that patients with rheumatoid arthritis had a greater risk of hospitalization for COPD compared to the general population. Some background Rheumatoid arthritis (RA) is...
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In a nutshell This study investigated if tofacitinib improves atherosclerosis in patients with rheumatoid arthritis. They found that tofacitinib improved disease activity and atherosclerosis in patients with rheumatoid arthritis. Some background Patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular (heart and circulatory...
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In a nutshell This study investigated if ultrasound of the hand can accurately detect inflammation in patients with rheumatoid arthritis in remission. They found that ultrasound detected inflammation in a high number of patients in clinical remission of rheumatoid arthritis. Some background Ultrasound (US) is used to determine if a patient with...
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In a nutshell This study investigated if intensifying treatment during low disease activity was beneficial in patients with rheumatoid arthritis (RA). They found that patients with low disease activity do not benefit from treatment intensification. Some background Management of rheumatoid arthritis (RA) involves treating patients with...
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In a nutshell This study reviewed data on clinical trials investigating the effects of certolizumab pegol (Cimzia) for the treatment of rheumatoid arthritis. They found that certolizumab pegol is an effective medication for the treatment of rheumatoid arthritis. Some background Rheumatoid arthritis (RA) is an autoimmune disease that causes...
Read MoreIn a nutshell This study investigated the patient reported outcomes (PRO) in patients receiving baricitinib (Olumiant) and methotrexate (Trexall). They found that patients receiving baricitinib had greater improvement in PRO compared to methotrexate alone. Some background Rheumatoid arthritis (RA) is an autoimmune disease where the...
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In a nutshell This study investigated if there is an increased risk of cancer in rheumatoid arthritis patients taking immunomodulating drugs. They found that there was no increased cancer risk in patients taking biological DMARDs compared to conventional synthetic DMARDs. Some background Rheumatoid arthritis (RA) is a chronic inflammatory...
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In a nutshell This study analyzed the safety of disease-modifying anti-rheumatic drugs (DMARDs) for the treatment of rheumatoid arthritis (RA). They found that patients taking biological DMARDs had a higher risk of infections compared to synthetic DMARDs. Some background Rheumatoid arthritis (RA) is an auto-immune condition which causes...
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In a nutshell This study investigated if baricitinib is a safe and effective medication for the treatment of rheumatoid arthritis. They found that baricitinib improved disease symptoms and was well-tolerated over a 128-week period. Some background Rheumatoid arthritis (RA) is a chronic inflammatory condition. In RA there is an increase in...
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