Welcome to Medivizor!

You're browsing our sample library. Feel free to continue browsing. You can also sign up for free to receive medical information specific to your situation.

Posted by on Nov 9, 2017 in Rheumatoid Arthritis | 0 comments

In a nutshell

This study investigated if ultrasound of the hand can accurately detect inflammation in patients with rheumatoid arthritis in remission.

They found that ultrasound detected inflammation in a high number of patients in clinical remission of rheumatoid arthritis.

Some background

Ultrasound (US) is used to determine if a patient with rheumatoid arthritis (RA) has inflammation or swelling in a joint. The severity of RA is rated using a Disease Activity Score measuring 28 joints (DAS28). Patients are said to be in clinical remission (non-active disease, mild to absent symptoms) when DAS28 is less than 2.6.

Some patients may be in clinical remission from RA and still have inflammation in certain joints. It is important to monitor this to determine if the condition may worsen. US may be useful for this purpose, however using US on all joints is time-consuming. 

Methods & findings

This study assessed using ultrasound to identify subclinical (no symptoms) inflammation in the hands of patients in remission from RA.

209 patients with RA were included in this study. Patients were assessed at the beginning of the study and 6 months and 12 months later. They were assessed using several disease activity measures including DAS28 and measurement of protein levels involved in inflammation.

US examination identified inflammation in joints of the hands of over 90% of patients in clinical remission at both 6 and 12 months.

The bottom line

This study concluded that ultrasound detected inflammation in a high number of patients in clinical remission of rheumatoid arthritis.

The fine print

The majority of participants in this study were female (81%). The results may not extend to the wider male population. Patients also had established RA and taking specific disease-modifying drugs (biological DMARDs). The results may not be applicable to recent onset RA or patients taking synthetic DMARDs.

What’s next?

If you have any concerns regarding treatment or monitoring of rheumatoid arthritis, please consult with your physician.

Published By :

Arthritis Research & Therapy

Date :

Oct 05, 2017

Original Title :

Ultrasound of the hand is sufficient to detect subclinical inflammation in rheumatoid arthritis remission: a post hoc longitudinal study.

click here to get personalized updates