In a nutshell This study investigated the safety and effectiveness of abatacept (Orencia) in combination with other medications to treat rheumatoid arthritis. The study concluded that abatacept in combination with conventional synthetic DMARDs was well tolerated and similarly effective as abatacept and methotrexate. Some background...
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In a nutshell This study investigated the safety of etoricoxib for the treatment of rheumatoid arthritis and osteoarthritis. They found that etoricoxib did not increase the risk of gastrointestinal adverse events. Some background Rheumatoid arthritis (RA) and osteoarthritis (OA) are conditions that cause painful swelling in the joins and bones of...
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The adrenal glands-which are also called suprarenal glands-are part of the endocrine system and are found on the top of each kidney. How the endocrine system hormones work Hormones secreted from glands of the endocrine system travel in the bloodstream to target cells. Target cells have receptors that are specific to each hormone. The hormones and receptors...
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In a nutshell This study investigated if the use of glucocorticoids during tofacitinib (Xeljanz) treatment has an impact on its ability to treat rheumatoid arthritis. They found that glucocorticoids did not negatively impact the effects of tofacitinib in treating rheumatoid arthritis. Some background Rheumatoid arthritis (RA) is a condition...
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In a nutshell This study investigated the level of disease activity following pregnancy in patients with juvenile arthritis. They found that disease activity was stable overall during the pregnancy and 12 months after delivery. Some background Juvenile idiopathic arthritis (JIA) is a condition that affects children aged under 18 and can persist into...
Read MoreIn a nutshell This study investigated if abatecept has an effect on bone mineral density in patients with rheumatoid arthritis. They found that patients taking abatacept have higher bone mineral density in the head of the femur bone. Some background Rheumatoid arthritis (RA) is chronic (long-term) condition that is caused by inflammation in...
Read MoreIn a nutshell This study investigated the effectiveness of a new drug, LBEC0101, for the treatment of rheumatoid arthritis. They found that LBEC0101 improved disease symptoms and was well tolerated by patients. Some background Rheumatoid arthritis (RA) is a chronic condition caused by the body’s immune system attacking tissue in the...
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In a nutshell This study reviewed the most recent evidence on the use of vaccinations in patients with rheumatoid arthritis. They found that vaccinations are generally well tolerated by patients undergoing treatment for rheumatoid arthritis. Some background Rheumatoid arthritis (RA) is a chronic (long-term) condition that is caused by the...
Read MoreIn a nutshell This study investigated the risk of malignancy in patients treated with biological disease-modifying drugs for rheumatoid arthritis (bDMARDs). They found that patients receiving bDMARDs to treat early rheumatoid arthritis have a reduced risk of malignancy overall. Some background Rheumatoid arthritis (RA) is a chronic condition...
Read MoreIn a nutshell This study investigated if a Mediterranean diet improved disease management in patients with rheumatoid arthritis. They found that a Mediterranean diet is associated with improvement in rheumatoid arthritis symptoms. Some background Rheumatoid arthritis (RA) is an inflammatory disease that causes painful swelling and degeneration...
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In a nutshell This study investigated if subcutaneous administration of tocilizumab is safe and effective in the long-term for the treatment of rheumatoid arthritis. They found that subcutaneous tocilizumab was well tolerated and improved disease symptoms. Some background Rheumatoid arthritis (RA) is a chronic condition that features painful...
Read MoreIn a nutshell This study investigated if body weight negatively affected the chance of achieving disease remission in patients with rheumatoid arthritis. They found that patients that were overweight or obese were less likely to achieve disease remission. Some background Rheumatoid arthritis (RA) is an autoimmune condition. This occurs...
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