In a nutshell This study investigated if an ultrasound of the joints (musculoskeletal) can predict if remission can be achieved in patients with rheumatoid arthritis (RA). They found that ultrasound can predict if a patient with RA will achieve remission. Some background The aim of treatment for rheumatoid arthritis (RA) is to reduce disease activity....
Read MoreIn a nutshell This phase 3 trial will evaluate the effectiveness of upadacitinib in patients with rheumatoid arthritis. The main outcome to be investigated is a change in disease activity. The details Rheumatoid arthritis (RA) is a chronic condition caused by painful swelling and inflammation in the joints. To treat RA, patients are prescribed...
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In a nutshell This phase 2 trial will investigate the safety and effectiveness of evobrutinib, a new treatment for rheumatoid arthritis. The main outcome will be the level of improvement in disease symptoms. The details Rheumatoid arthritis (RA) is a chronic condition caused by painful swelling and inflammation in the joints. Patients are...
Read MoreIn a nutshell This phase 2 trial will evaluate the safety and effectiveness of pirfenidone (Esbriet) for the treatment of interstitial lung disease in patients with rheumatoid arthritis. The main outcome to be investigated is the level of lung disease progression. The details Although rheumatoid arthritis (RA) primarily affects the joints,...
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In a nutshell This study investigated if there are disease features that can predict if a patient with rheumatoid arthritis will respond well to methotrexate treatment. They found that higher disease activity at early stages of treatment predicted a poor treatment response in these patients. Some background Treatment of rheumatoid arthritis (RA)...
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Prior to the 20th century, most people lived about 47 years in the developed world because of infectious diseases. In 1940, the first use of penicillin to treat infectious diseases occurred and penicillin became available in 1945 to the general public. Science and research conducted throughout the 1950s, 60s, and 70s, created more antibiotics so that life...
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In a nutshell This study investigated fatigue in patients with early-stage rheumatoid arthritis. They found that these patients commonly report fatigue and this was linked to higher depression and anxiety scores. Some background The aim of rheumatoid arthritis (RA) treatment is to reduce disease activity. To achieve this, a patient will be...
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When we posted, “What’s in a name? Rheumatoid Arthritis versus Rheumatoid Disease,”we featured Kelly Young, a mom on a crusade to change thinking about an autoimmune disease that attacks the connective tissue of joints and systemically attacks the organs of the body – rheumatoid disease. Rheumatoid disease (also known as rheumatoid...
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In a nutshell This study investigated whether tocilizumab (Actemra) treatment improves work productivity in patients with rheumatoid arthritis. They found that house workers treated with tocilizumab were more productive and better quality of life compared to patients taking synthetic disease-modifying drugs. Some background One of the...
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In a nutshell This study investigated if an infliximab (Remicade) biosimilar is safe and effective to treat rheumatoid arthritis. They found that the infliximab biosimilar PF-06438179/GP1111 was similarly effective as standard infliximab and well tolerated. Some background Biosimilars are medicines that act in the same way as the original...
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In a nutshell This study investigated the timepoint at which certolizumab pegol treatment is effective in treating rheumatoid arthritis. They found that the effectiveness of certolizumab pegol treatment at 12 weeks predicts future treatment success at 52 weeks. Some background Certolizumab pegol (CZP) is a new biologic drug that blocks activity of...
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In a nutshell This study investigated whether upadacitinib is a safe and effective treatment for unresponsive patients with rheumatoid arthritis (RA). They concluded that upadacitinib improved RA symptoms in combination with csDMARDs and was well tolerated. Some background ne type of medication used to treat rheumatoid arthritis...
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