In a nutshell This study investigated the benefit of local therapies as first-line interventions for metastatic prostate cancer. Authors reported improved survival with radiation and surgery among men with metastatic prostate cancer at diagnosis. Some background Metastatic prostate cancer is cancer that has spread to distant parts of the body. The...
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Guidelines for prostate cancer disease staging and treatment
In a nutshell This study summarized updated guidelines for risk assessment and appropriate management approaches for prostate cancer. Some background Treatment options for prostate cancer require careful assignment of patients to risk groups. The tumor stage (extant of disease) is determined by rectal examinations and imaging results. A...
Read MoreCombining chemotherapy and hormone therapy early for metastatic prostate cancer
In a nutshell This study examined the safety and effectiveness of androgen deprivation therapy (ADT) plus docetaxel (Taxotere) compared to ADT alone for metastatic prostate cancer. Researchers reported increased progression-free survival and overall survival when ADT was combined with docetaxel. Some background ADT is a type of hormone therapy...
Read MoreDecline in circulating tumor cells during treatment associated with better survival
In a nutshell This study examined the link between circulating tumor cells (CTCs) and treatment outcome in metastatic castration-resistant prostate cancer (mCRPC). Authors reported better survival outcomes for mCRPC patients with a significant decline in CTC count during treatment. Some background Metastatic castration-resistant prostate...
Read MoreNow less invasive: Imaging-guided radiation techniques for prostate cancer
In a nutshell This study compared the safety and effectiveness of two forms of imaging-guided radiation techniques for prostate cancer. Researchers reported more favorable outcomes with intensity modulated radiation therapy (IMRT) than with 3-dimensional conformal radiation therapy (3DCRT). Some background Radiation therapy is a common treatment...
Read MoreWatching but not treating (active surveillance) low-risk prostate cancer
In a nutshell The authors determined the benefits and pitfalls of active surveillance (AS). The authors concluded that AS may reduce over-treatment in low-risk prostate cancer patients without compromising 10-year prostate cancer survival. Some background AS is a form of non-treatment used in prostate cancer patients who are low-risk. This...
Read MorePotential predictor of treatment outcomes for metastatic castration-resistant prostate cancer
In a nutshell This study analyzed predictors of treatment outcomes for metastatic castration-resistant prostate cancer (mCRPC). Researchers concluded that testosterone levels before treatment can help predict overall survival in men with mCRPC. Some background Hormone therapy is the standard of care for advanced prostate cancer, including...
Read MoreDifferent doses and combinations of external beam radiation therapy examined
In a nutshell This study compared different external beam radiation therapy (EBRT) approaches for localized prostate cancer. Authors reported high effectiveness with higher doses of radiation therapy, particularly when hormone therapy was added to treatment. However, these combinations were also associated with the highest rate of side effects. Some...
Read MoreAfter Cancer Treatment: Living Out The Cure
When you’re 8 years old, jumping rope, playing dolls, swinging on swing sets and doing homework are girlhood pursuits. Discovering “Lumpy Luey” in your left chest wall isn’t. In 1978, Stephanie Dodds’ way of coping with the diagnosis of Ewing Sarcoma was to give it a name and focus on “getting rid of it.”...
Read MoreSearching for overweight men with low-risk prostate cancer undergoing active surveillance
In a nutshell This phase 3 trial aims to evaluate the benefit of a diet and exercise program in overweight men with low-risk prostate cancer. The main outcome to be investigated is a change in blood sugar metabolism in prostate cancer cells. The trial is recruiting in Seattle (Washington), USA. The details Low-risk prostate cancer is often managed...
Read MoreTwo thermal techniques compared for localized prostate cancer
In a nutshell This study compared the safety and effectiveness of two alternative treatment options for localized prostate cancer. Researchers reported comparable treatment effectivity for high-intensity focused ultrasound (HIFU) and cryoablation. However, HIFU was overall associated with fewer side effects. Some background Localized prostate...
Read MoreA Review of Prostate Cancer Prognostic Factors
Prognostic factors, including blood tests and radiographic scans, can help establish a patient’s prognosis and determine a treatment path. Experts from MD Anderson Cancer Center, Drs. Jeri Kim and Sumit Subudhi, review factors that are associate with prostate cancer and discuss research underway that could lead to more personalized...
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