In a nutshell This study aimed to evaluate the use of abiraterone (Zytiga) and olaparib (Lynparza) in advanced prostate cancer. This study concluded that olaparib in combination with abiraterone provided clinical benefit for patients with metastatic castration-resistant prostate cancer compared with abiraterone alone. Some background...
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Should men with castration-resistant metastatic prostate cancer receive further hormone therapy?
In a nutshell This study aimed to discover the optimal timing of hormone therapies in combination with androgen-deprivation therapy (ADT) for patients with metastatic hormone-sensitive prostate cancer. This study found that treatment with a second hormone therapy after prostate cancer becomes immune to hormone treatment is associated...
Read MoreSide-effects and quality of life changes after robotic prostate surgery
In a nutshell This study aimed to evaluate short and medium-term patient-reported side-effects after robotic prostate surgery. This study found that patient-reported outcome measures evaluating urinary symptoms and health related quality of life do not significantly change after robotic prostate surgery. Some background...
Read MoreCan PET/CT scanning guide radiotherapy treatment in prostate cancer?
In a nutshell This paper studied if a targeted form of radiotherapy could be effective in improving patient outcomes after surgical treatment of prostate cancer. The main finding was that a specific type of radiotherapy using PET scans improved outcomes in these patients. Some background Prostate specific antigen is a chemical in the blood that has...
Read MoreCancer Vaccines
When I think of vaccines, I think of the MMRV (measles, mumps, rubella and varicella) vaccines which help our bodies establish immunity against diseases that used to kill. Now, there are vaccines being created for cancer. The rise of cancer vaccines According to Dr. Nora Disis, an oncologist and researcher in cancer vaccines at the University of...
Read MoreRadiotherapy treatments for patients with prostate cancer
This study compared the outcome of low-dose rate brachytherapy (LDR-BT) and image-guided intensity-modulated radiotherapy (IG-IMRT) for different severities of localized prostate cancer. Five year survival rates will almost the same across both treatments. Five year biochemical failure free survival rates were higher for patients treated with LDR-BT...
Read MoreOutcomes of palliative resections of the prostate in patients with locally advanced prostate cancer
In a nutshell This study aimed to evaluate the usefulness of transurethral resection of the prostate (TURP). This study found that TURP is a surgical option to relieve bladder obstruction in patients with locally advanced prostate cancer. Some background Advanced prostate cancer may cause significant complications which affect...
Read MoreDo side-effects vary between risk groups after treatment for localized prostate cancer?
In a nutshell This study aimed to determine whether differences in side effects reported over time in patients who had surgery or radiotherapy varied by risk group. This study found that for men with low-risk prostate cancer, radiotherapy was associated with higher sexual function scores at 3 years than surgery;...
Read MoreQuality of life during treatment with chemotherapy and hormonal therapy
In a nutshell This study aimed to compare quality of life between patients with metastatic prostate cancer who were treated with androgen deprivation therapy (ADT) and docetaxel and those who were treated with ADT alone. This study found that ADT and docetaxel was associated with statistically worse QOL at 3 months. However, QOL was better...
Read MoreComparing radiotherapy treatment regimens for prostate cancer
In a nutshell This study aimed to evaluate two different timelines of delivering radiotherapy, 56 Gy delivered in 16 treatments or 67 Gy delivered in 25 treatments, to the prostate. This study found that both treatments are safe and effective in the treatment of prostate cancer. Some background Hypo-fractionated radiation therapy...
Read MoreLooking for prostate cancer survivors experiencing fatigue after treatments
In a nutshell This trial is examining the effectiveness of a 12-week Body-Mind Training (BMT) for prostate cancer survivors. The main outcome to be measured will be the change in fatigue levels. This trial is being conducted in Albuquerque, New Mexico. The details Cancer survivors over the age of 55 may have challenges coping...
Read MoreSearching for patients with biochemical recurrence of prostate cancer
In a nutshell This trial is examining the effectiveness of Gallium-68 PSMA-11 PET imaging for determining the presence of metastatic prostate cancer. The main outcome to be measured is the detection of tumor location which will be confirmed by conventional follow-up. This study is being conducted in the UCSF Imaging Center in San...
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