In a nutshell This study examined the difference between early and late relapses in patients with diffuse large B-cell lymphoma. The authors concluded that patients who experience a late relapse have better outcomes than those who experience early relapse. Some background Diffuse large B-cell lymphoma (DLBCL) is a type of non-Hodgkin lymphoma. It...
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Marathons are grueling 26.2 mile treks. The Boston Marathon is the oldest (started in 1897) and is one of the Marathon Majors (along with London, New York, Tokyo, Berlin and Chicago). Marathon Man Raising Money For LLS In 2001, at age 48, family practitioner, Larry Saltzman ran his first marathon in Chicago. That started a 13 marathon odyssey to...
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This summer has been a challenge after a family member with celiac disease had a gluten exposure (Click here to read more about celiac disease). Gluten damages the small intestine villi (see 5 Facts You Probably Didn’t Know About Your Small Intestines), which are essential for nutrition absorption. For over a month, gastrointestinal pain, vomiting...
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Last summer we provided a series of posts on oncology basics. Oncology Basics: Preparing for ASCO covered some of the history of oncology. In Understanding Cells, we reviewed what is newly understood about cells–it’s way beyond what you learned in high school biology. DNA with lots of animated videos also explained some of the basics...
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In April, the American Association for Cancer Research (AACR) held a free education event on cancer called Progress and Promise Against Cancer in Washington, D.C. Surrounded by experts in cancer research, Kim Hall Jackson shared her patient story. One evening in 2008, Jackson, an event planner, was running the mayor’s inaugural event in...
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“I am 24 years old. Last year on January 15th 2016, I was diagnosed with Stage 2A Classical Nodular Sclerosing Hodgkin’s Lymphoma. I had 12 cycles of ABVD chemotherapy over 6 months and went into complete remission on August 8th, 2016. A few weeks before my wedding, on November 4th 2016 I had my first follow up CT scan which showed enlarged...
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In a nutshell This study explored the long-term health outcomes of adult survivors of childhood non-Hodgkin lymphoma (NHL) patients. The authors determined that adult survivors have a high rate of chronic health conditions. Some background Long-term survival of childhood NHL has increased due to improvements in treatment options. An understanding...
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In a nutshell This study reviewed the use of stem cell (immature blood cell) transplantation in follicular lymphoma. Some background New treatment options have improved survival in follicular lymphoma patients. Improvements in stem cell transplantation (SCT) have also led to increased survival. Typically only younger patients have been able to...
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In a nutshell This study examined the use of the combination of bendamustine (Treanda) and rituximab (Rituxan) as a firstline treatment in patients with follicular or mantle cell lymphoma. This study concluded that this treatment combination was more effective than the standard treatment of rituximab plus CHOP chemotherapy. Some background The...
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In a nutshell This study examined the use of ibrutinib (Imbruvica) combined with the chemotherapy combination R-CHOP in untreated diffuse large B-cell lymphoma. This study determined that ibrutinib was safe and effective when added to R-CHOP. Some background R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) is a...
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In a nutshell The authors investigated the use of carboplatin instead of cisplatin in the DHAP chemotherapy regimen. The authors concluded that carboplatin is less toxic than cisplatin, and may be a good substitute. Some background Non-Hodgkin lymphomas (NHLs) include all types of lymphoma except for...
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In a nutshell This study developed a method of predicting prognosis for patients with advanced mantle cell lymphoma (MCL). The authors concluded that the MCL International Prognostic Index (MIPI) was more accurate for MCL compared to those developed for other types of lymphoma. Some background Mantle cell lymphoma (MCL) is an uncommon form of...
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