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Comparison between two standard treatments for transplant-ineligible multiple myeloma

Posted by on Aug 2, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study investigated whether a combination of bortezomib (Velcade), melphalan (Alkeran) and prednisone (Deltasone) was more effective than lenalidomide (Revlimid) and dexamethasone (Decadron) followed by lenalidomide maintenance for newly diagnosed multiple myeloma (MM). The main finding was that age and disease risk influenced the...

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Looking for patients with relapsed multiple myeloma to test a biological drug and immune cell vaccine

Posted by on Jul 31, 2019 in Multiple Myeloma | 0 comments

In a nutshell This trial is investigating the effectiveness and side effects of nivolumab (Opdivo) with a dendritic cell vaccine for patients with multiple myeloma (MM). The main outcome of this study would be to see the number of patients that develop an allergic reaction to the treatment. This study is recruiting in Boston, MA, United...

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Searching for patients to try combinations of treatments for newly diagnosed multiple myeloma.

Posted by on Jul 29, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study is looking for patients with newly diagnosed multiple myeloma (MM) to try different treatment regimens. The main outcome that will be measured is the number of patients who do not experience cancer worsening after treatment. This trial is recruiting in Chicago, Illinois, United States. The details There are several...

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Does age influence the safety and effectiveness of stem cell treatment for patients with multiple myeloma?

Posted by on Jul 14, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study examined the safety and effectiveness of stem cell transplantation (SCT) in elderly patients with multiple myeloma (MM) aged 65 or older compared to younger patients. The authors concluded that SCT was equally as safe and effective for patients in both age groups. Some background Multiple myeloma is a complex type of...

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Carfilzomib, thalidomide and dexamethasone in the treatment of multiple myeloma

Posted by on Jul 14, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study looked at the safety and effectiveness of carfilzomib (Kyprolis), thalidomide (Thalomid) and dexamethasone (Decadron) in the treatment of patients with multiple myeloma. Researchers concluded that this treatment plan is safe and effective in these patients. Some background Multiple myeloma is a cancer of the bone marrow. It is...

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Evaluating ixazomib maintenance therapy for patients with multiple myeloma

Posted by on Jun 30, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of ixazomib (Ninlaro) maintenance therapy in patients with multiple myeloma (MM). This study concluded that ixazomib is a safe and effective maintenance therapy for these patients. Some background Multiple myeloma is a type of cancer of the bone marrow that can lead to abnormal...

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Nanodrugs

Nanodrugs

Posted by on Jun 29, 2019 in Blog, Breast cancer, Colorectal cancer, Lung cancer, Lymphoma, Melanoma, Multiple Myeloma, Non-Hodgkin lymphoma, Parkinson's Disease, Prostate cancer | 0 comments

Nanodrugs have been around for some time. In fact, over 250 drugs using nanotechnology that  have been approved by the FDA and are in clinical use. The name nanodrug or nanopharmaceuticals refers to the size of the particle that is created to house the medication. A nano is very tiny: nanoparticles are between 1 and 100 nanometers in at least one of its...

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Searching for patients with recurrent multiple myeloma to test daratumumab

Posted by on May 24, 2019 in Multiple Myeloma | 0 comments

In a nutshell This phase 2 trial is evaluating how well daratumumab (Darzalex) works in treating patients with multiple myeloma (MM) that has come back after a stem cell transplant (SCT). The main outcome to be measured will be the number of patients who have a complete disappearance of all signs of cancer. This trial is recruiting in Houston,...

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Evaluating busulfan plus melphalan conditioning for patients with multiple myeloma before stem cell transplantation

Posted by on May 20, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of busulfan (Myleran) plus melphalan (Alkeran) compared to melphalan alone for patients with multiple myeloma (MM) before autologous stem cell transplantation (ASCT). This study concluded that the combination treatment was more effective for these patients. Some background...

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