In a nutshell This paper compared the effect of denosumab (Prolia) and zoledronic acid (Zometa) in patients with newly diagnosed multiple myeloma. Denosumab could be considered in patients with newly diagnosed multiple myeloma. Some background Multiple myeloma is a cancer of the plasma cells of the blood. Multiple myeloma can cause bone...
Read MoreIn a nutshell This paper compared the effect of carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone (Ozurdex) to lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma. The addition of carfilzomib was associated with a longer survival. Some background Multiple myeloma is a cancer of the...
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In a nutshell This paper compared the safety and effectiveness of daratumumab (Darzalex) in combination with bortezomib (Velcade) and dexamethasone (Ozurdex) in patients with relapsed or refractory multiple myeloma. Some background Multiple myeloma is a cancer of the plasma cells of the blood. Multiple myeloma can be refractory (not responding...
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In a nutshell This paper studied the risk of stroke in patients with newly diagnosed multiple myeloma. The risk of stroke is increased in patients with certain type of multiple myeloma and a high creatinine level. Some background Multiple myeloma is a cancer of the plasma cells of the blood. The risk of a stroke is higher in patients with...
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In a nutshell This study aims to test the safety and effectiveness of daratumumab in combination with carfilzomib, lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma. The main outcome to be measured will be the presence of disease. This study is being conducted in New Jersey, and New York. The details Multiple...
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In a nutshell This study aims to compare ixazomib plus dexamethasone versus pomalidomide plus dexamethasone on survival in participants with relapse and/or refractory multiple myeloma. The outcome to be measured is the duration of time until disease progresses (worsens). The details Multiple myeloma is a cancer of the plasma cells in the...
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In a nutshell This study aims to compare bortezomib, lenalidomide, and dexamethasone with carfilzomib, lenalidomide, and dexamethasone. The outcome to be measured is the overall survival (time from treatment until death from any cause). The details Multiple myeloma is a cancer of the plasma cells in the blood. Treatment for multiple myeloma...
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Cherry Hughes** is an active, energetic 75 year old, still working in the marketing and public relations profession in Great Britain. Her life is filled with friends and fun. “I love cooking and eating out. I am deeply interested in politics. I love music …I go to jazz clubs. I love going to France …I have a little apartment...
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In a nutshell This paper studied the outcome of weekly carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma who cannot be treated with transplant. The authors concluded that this combination was effective in these patients. Some background Multiple myeloma is a cancer of the plasma cells of the blood....
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There are 1.6 million people diagnosed with cancer in the US each year. Of these, 650,000 receive chemotherapy. Did you know that 60,000 people a year are hospitalized for neutropenia, a common side effect of chemotherapy? One in fourteen die because of it. Of the 650,000 receiving chemotherapy, 104,000 are not aware of neutropenia and 52,000 don’t...
Read MoreIn a nutshell This study aimed to evaluate post-traumatic stress disorder (PTSD) in patients who have had treatment for cancer. This study found that a number of patients undergoing cancer treatment developed PTSD after treatment and recommended that supports are put in place. Some background Post-traumatic stress disorder (PTSD) is a...
Read MoreIn a nutshell This study aimed to evaluate post-traumatic stress disorder (PTSD) in patients who have had treatment for cancer. This study found that a number of patients undergoing cancer treatment developed PTSD after treatment and recommended that supports are put in place. Some background Post-traumatic stress disorder (PTSD) is a...
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