In a nutshell This study evaluated the safety and effectiveness of bortezomib (Velcade) and lenalidomide (Revlimid) for patients with multiple myeloma after stem cell transplantation. This study found this combination is effective for these patients, with few side effects. Some background Multiple myeloma (MM) is a type of cancer...
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In a nutshell This study evaluated the safety and effectiveness of bortezomib (Velcade) and lenalidomide (Revlimid) for patients with multiple myeloma after stem cell transplantation. This study found this combination is effective for these patients, with few side effects. Some background Multiple myeloma (MM) is a type of cancer...
Read MoreIn a nutshell This study evaluated the outcomes of maintenance therapy with lenalidomide (Revlimid) after autologous stem cell transplantation (ASCT) in patients with multiple myeloma (MM). This study concluded that longer lenalidomide maintenance leads to improved survival outcomes in these patients. Some background Multiple myeloma is a type of...
Read MoreIn a nutshell This trial will investigate the effects of bb2121 in patients with non-responsive multiple myeloma (MM) who have progressed after standard treatment. The percentage of patients who respond and the percentage of patients who respond completely will be the main measures in this study. This study will take place in the United States and...
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In 1904, a physician wrote about a patient with leukemia who went into remission when he got the flu. Though the patient was not cured, it was a ray of hope at a time when there were no treatments for leukemia. Other cases were reported throughout the years of people with Burkitt’s Lymphoma and Hodgkin’s Lymphoma going into remission when they...
Read MoreIn a nutshell This trial is comparing the effectiveness of a new therapy, bb2121, to commonly used combinations of drugs for relapsing/refractory (unresponsive) multiple myeloma (RRMM). The main outcome to be measured is the time from the start of treatment until cancer worsens. The details Many patients are cured with standard treatments, such as...
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In a nutshell This study compared the effects of stem cell transplant to other newer treatments for recently diagnosed multiple myeloma (MM). The main finding was patients who received stem cell transplant had better outcomes than those who did not. Some background Stem cell transplant involves the transfer of cells to a patient. This is an effective...
Read MoreIn a nutshell This article investigated the long-term safety and effectiveness of tandem autologous/allogeneic hematopoietic cell transplantation (auto/alloHCT) for patients with multiple myeloma (MM). The authors concluded that this therapy is safe and can improve the overall survival of these patients. Some background...
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In a nutshell This study monitored the development of minimal residual disease (MRD) after transplant for multiple myeloma (MM). The main finding was that different patterns of MRD development are associated with varying success after stem cell transplant for MM. Some background There are many treatments for MM. Patients are often cured fully by...
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During July and early August of 2018, the Harris Poll in association with the American Society of Clinical Oncologists (ASCO’s) conducted a poll of 4,887 U.S. adults, 1001 of these have or had cancer. This second annual National Cancer Opinion Survey explored a wide range of topics. The findings clearly describe disparities in the care patients with...
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In a nutshell This article investigated the safety and effectiveness of pomalidomide (Pomalyst) for the treatment of relapsed or refractory (does not respond to treatment) multiple myeloma (RRMM) in a real-life setting. The authors concluded that this treatment is safe and effective in these patients. Some background Multiple myeloma...
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In a nutshell This study investigated the effect of kidney problems on the success of stem-cell transplant for Multiple Myeloma (MM). The main finding was that the stage of the kidney problems did not impact the effects of stem-cell transplant. Some background Stem-cell transplant involves the transfer of cells to a patient. It is commonly used in the...
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