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Modern drug therapies versus surgery of metastasis in melanoma that has spread

Posted by on Jul 21, 2019 in Melanoma | 0 comments

In a nutshell This study wanted to find out if advances in the treatment of melanoma over the last 60 years have had an impact on the survival of patients. The study found that while modern drug therapy improves survival, the most effective approach is to surgically remove the tumors that have spread through the body. Some background Melanoma can be...

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Timing of treatment with ipilimumab and nivolumab in patients with stage 3 melanoma

Posted by on Jul 8, 2019 in Melanoma | 0 comments

In a nutshell This study wanted to find out what the best timing is for treating patients with stage 3 melanoma with ipilimumab (Yervoy) and nivolumab (Opdivo). The study found that the best timing was two cycles of ipilimumab 1 mg/kg plus nivolumab 3 mg/kg every three weeks. Some background Ipilimumab and nivolumab are medications used to treat...

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Posted by on Jun 29, 2019 in Blog, Breast cancer, Colorectal cancer, Lung cancer, Lymphoma, Melanoma, Multiple Myeloma, Non-Hodgkin lymphoma, Parkinson's Disease, Prostate cancer | 0 comments

Nanodrugs have been around for some time. In fact, over 250 drugs using nanotechnology that  have been approved by the FDA and are in clinical use. The name nanodrug or nanopharmaceuticals refers to the size of the particle that is created to house the medication. A nano is very tiny: nanoparticles are between 1 and 100 nanometers in at least one of its...

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Looking patient with advanced melanoma to test a new drug

Posted by on Jun 28, 2019 in Melanoma | 0 comments

In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced melanoma and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details...

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Long-term outcomes for dabrafenib plus trametinib treatment for metastatic melanoma.

Posted by on Jun 23, 2019 in Melanoma | 0 comments

In a nutshell This study wanted to find out how well patients with advanced melanoma with mutations (abnormal genes) survive when treated with dabrafenib (Tafinlar) and trametinib (Mekinist) combination. The study found that long term, patients survived moderately well with this treatment. Some background Advanced melanoma can be hard to treat. In...

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Restaging warranted prior to adjuvant therapy in patients with resected stage IIIB and IIIC melanoma.

Posted by on May 31, 2019 in Melanoma | 0 comments

In a nutshell This article investigated the need for restaging in patients with stage IIIB and IIIC melanoma before starting adjuvant therapy (AT; treatment after surgery).   The authors concluded that restaging should be considered for these high-risk patients before starting the AT.  Some background Melanoma a type of skin cancer...

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