In 1904, a physician wrote about a patient with leukemia who went into remission when he got the flu. Though the patient was not cured, it was a ray of hope at a time when there were no treatments for leukemia. Other cases were reported throughout the years of people with Burkitt’s Lymphoma and Hodgkin’s Lymphoma going into remission when they...
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T-VEC treatment in patients with melanoma
In a nutshell This study wanted to find out how well a new cancer treatment called T-VEC works in patients with melanoma that cannot be surgically removed. The study found that this treatment is very effective in patients with melanoma that cannot be surgically removed. Some background T-VEC is short for talimogene laherparepvec. This is a new type of...
Read MoreComparing safety and effectiveness of treatments for advanced melanoma
In a nutshell This study wanted to look at the different types of treatment for melanoma, and find out which was best and had the least side effects. The study found that the best treatment was to use MEK inhibitors and BRAF, as it worked the best and had the least side effects. Some background There are a number of treatments available for melanoma...
Read MoreReal-world safety and effectiveness of BRAF inhibitors and anti-CTLA4 antibody in melanoma
In a nutshell This article investigated the safety and effectiveness of BRAF inhibitors like vemurafenib (Zelboraf) and dabrafenib (Tafinlar) and immunotherapy such as ipilimumab (Yervoy) in a real-world setting for patients with advanced melanoma. The authors concluded that this therapy is safe and...
Read MoreIsolated limb perfusion in patients with spreading melanoma
In a nutshell This study looked at the safety and effectiveness of repeated limb perfusion with anti-cancer drugs for patients with melanoma work. The study found that repeated limb perfusion is safe, and has a similar rate of success to the first time the limb was perfused. Some background Isolated limb perfusion (ILP) is a technique...
Read MoreIsolated limb perfusion in patients with spreading melanoma
In a nutshell This study looked at the safety and effectiveness of repeated limb perfusion with anti-cancer drugs for patients with melanoma work. The study found that repeated limb perfusion is safe, and has a similar rate of success to the first time the limb was perfused. Some background Isolated limb perfusion (ILP) is a technique...
Read MoreASCO’s National Cancer Opinion Survey Results
During July and early August of 2018, the Harris Poll in association with the American Society of Clinical Oncologists (ASCO’s) conducted a poll of 4,887 U.S. adults, 1001 of these have or had cancer. This second annual National Cancer Opinion Survey explored a wide range of topics. The findings clearly describe disparities in the care patients with...
Read MoreEvaluating epacadostat and pembrolizumab in patients with advanced melanoma
In a nutshell This article investigated the safety and effectiveness of epacadostat and pembrolizumab (Keytruda) for patients with advanced melanoma. The authors concluded that this therapy is safe and has encouraging effectiveness in these patients. Some background The immune system normally works to detect...
Read MoreSearching for patients with untreated melanoma that has spread to trial a new treatment
In a nutshell This trial aims to test the safety and effectiveness of adding a new drug called NKTR-214 to treatment with nivolumab (Opdivo) is better than just using nivolumab alone. The main outcomes that will be measured are how many people respond to treatment, how long the patients go without cancer growing or spreading, and overall...
Read MoreLooking for patients with melanoma to test a new medication
In a nutshell This trial is examining the effectiveness of a new medication for treating melanoma called Daromun, given before surgery. The main outcome to be measured will be survival without cancer. This study is being conducted in Tampa, Florida, the United States. The details Surgery is one of the main treatments for...
Read MoreTiredness in survivors of melanoma
In a nutshell This study wanted to find out if people who have survived having melanoma cancer have higher levels of tiredness (fatigue) compared to those who have not had cancer. The study found that the people who survived having melanoma who were under 40 years old had slightly higher levels of fatigue compared to the general population. Some...
Read MoreEvaluating pembrolizumab in patients with melanoma spread to the brain
In a nutshell This article investigated the safety and effectiveness of pembrolizumab (Keytruda) for patients with melanoma and untreated brain metastasis (the spread of cancer cells from the place where they first formed to another part of the body). The authors concluded that this therapy is safe and can improve the...
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