In a nutshell This study compared stereotactic body radiation therapy (SBRT) and thermal ablative procedures (TAP) in early-stage non-small cell lung cancer (NSCLC). They found that overall survival (OS) was greater in SBRT-treated patients. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung...
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Nanodrugs have been around for some time. In fact, over 250 drugs using nanotechnology that have been approved by the FDA and are in clinical use. The name nanodrug or nanopharmaceuticals refers to the size of the particle that is created to house the medication. A nano is very tiny: nanoparticles are between 1 and 100 nanometers in at least one of its...
Read MoreIn a nutshell This phase 1/2 trial will investigate the safety of 9-ING-41, for treatment-resistant cancers. The main outcome will be the number of treatment-related adverse events (TRAEs). This trial is recruiting in the United States. The details Some cancers may not respond to conventional treatment. Treatment-resistant cancers are called...
Read MoreIn a nutshell This phase 2 trial will investigate the effectiveness of stereotactic body radiotherapy (SBRT) in patients with metastatic cancer. The main outcome will be progression-free survival (PFS; survival without the cancer getting worse). This trial is recruiting in multiple locations in New York and New Jersey, US. The details...
Read MoreIn a nutshell This study wanted to find out if treating recurrent non-small cell lung cancer with ramucirumab (Cyramza) and pembrolizumab (Keytruda) works better than standard care practices. The main outcome that will be measured is the overall survival rates. This study will take place in the United States. The details There are a...
Read MoreIn a nutshell This study wants to find out how well talazoparib (Talzenna) and temozolomide (Temodal) work for treating patients with small cell lung cancer that has come back after or was unresponsive to initial chemotherapy. The main outcome that will be measured is how long the patients go before the cancer grows. The study is...
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In a nutshell This phase 1 study will investigate the dose range and effectiveness of an experimental drug, XmAb23104, in the treatment of advanced lung cancer and other solid tumors. The main outcome will be the safety and tolerability of XmAb23104. This trial is recruiting in Georgia, Texas, and Virginia, the United States. The details Advanced...
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In a nutshell This study investigated if postoperative radiotherapy (PORT) is effective in non-small cell lung cancer (NSCLC) after pneumonectomy (PMT; lung surgery). They found that PORT improved survival and was well tolerated in these patients. Some background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer....
Read MoreIn a nutshell This phase 2 trial is examining the effectiveness and safety of navarixin (MK-7123) in combination with pembrolizumab (Keytruda) in patients with non-small cell lung cancer (NSCLC). The main outcome to be measured will be the objective response rate (ORR; tumor shrinkage or disappearance). The details A treatment option for...
Read MoreIn a nutshell This phase 2 trial will investigate the safety and effectiveness of durvalumab (Imfinzi) in patients with stage III non-small cell lung cancer (NSCLC). The main outcomes will be the number of treatment-related adverse events (TRAEs) and progression-free survival (PFS). The details Non-small cell lung cancer (NSCLC)...
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In a nutshell This study wanted to find out if certain levels of compounds in the blood could predict survival in patients with non-small cell lung cancer (NSCLC). The study found that levels of some of the compounds tested were related to how well the patients survived. Some background The levels of certain compounds in the blood are tested...
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In a nutshell This study examined the effects of exercise at home in patients with non-small cell lung cancer (NSCLC). This study found that the at-home exercise program had multiple fitness benefits and was tolerated by most patients. Some background Exercise is important for patients with lung cancer. Exercise is associated with...
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