In a nutshell This trial is comparing the safety and effectiveness of venetoclax (Venclexta) and azacitidine (Vidaza) with azacitidine alone in patients with acute myeloid leukemia (AML). The main outcome to be measured will be overall survival. Complete remission (no signs of cancer after treatment) will also be measured. The details Acute...
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Searching for patients with blood cancer to test new stem cell transplant option
In a nutshell This phase 3 trial is comparing the safety and effectiveness of NiCord stem cell treatment with stem cells taken from the umbilical cord. The main outcome to be measured is the time to neutrophil engraftment (white blood cells accepted by the body that start to grow and make new cells) following transplantation. The details...
Read MoreASCO’s National Cancer Opinion Survey Results
During July and early August of 2018, the Harris Poll in association with the American Society of Clinical Oncologists (ASCO’s) conducted a poll of 4,887 U.S. adults, 1001 of these have or had cancer. This second annual National Cancer Opinion Survey explored a wide range of topics. The findings clearly describe disparities in the care patients with...
Read MoreIs reducing the dose of imatinib effective in the treatment of chronic myeloid leukemia?
In a nutshell This study looked at the effectiveness of reducing the dose of imatinib (Gleevec) in the treatment of chronic myeloid leukemia (CML). Researchers found that a lower dose of imatinib can achieve the same result as a high dose in most patients. Some background Chronic myeloid leukemia (CML) is a cancer of the bone marrow. This leads to...
Read MoreArsenic trioxide and Realgar-Indigo naturalis formula for children with leukemia
In a nutshell This study compared arsenic trioxide (ATO; Trisenox) with the Realgar-Indigo naturalis formula (RIF) in the treatment of children with acute promyelocytic leukemia (APL). Researchers found that oral RIF is as safe and effective as intravenous (IV) ATO in the treatment of these patients. Some background Acute promyelocytic...
Read MoreCan pretreatment with obinutuzumab reduce side effects of CLL treatment?
In a nutshell This study looked at the use of obinutuzumab (Gazyva) pretreatment to reduce side effects of chemotherapy in patients with chronic lymphocytic leukemia (CLL). Researchers found that obinutuzumab pretreatment is effective in reducing chemotherapy side effects in these patients. Some background Treatment of CLL involves...
Read MoreMitoxantrone chemotherapy for adults with acute myeloid leukemia
In a nutshell This study wanted to assess the safety and effectiveness of high dose mitoxantrone (Novantrone) in the treatment of acute myeloid leukemia. Researchers found that mitoxantrone is safe and effective in these patients. Some background Acute myeloid leukemia (AML) is a cancer of the bone marrow. It leads to abnormal immune cells....
Read MoreCan molecular monitoring help treatment and outcomes in patients with chronic myeloid leukemia?
In a nutshell This study looked at the use of molecular monitoring to assess outcomes in patients with chronic myeloid leukemia. Researchers found that molecular monitoring at 3 and 12 months is beneficial to these patients. Some background Chronic myeloid leukemia (CML) is a cancer of the bone marrow. This leads to an abnormal immune system and...
Read MoreEvaluating ibrutinib and obinutuzumab combination for the treatment of chronic lymphocytic leukemia
In a nutshell This study aimed to investigate the effectiveness of ibrutinib and obinutuzumab combination in patients with chronic lymphocytic leukemia. This study concluded that this combination is safe and highly effective as a treatment for these patients. Some background Obinutuzumab (Gazyva) and ibrutinib (Imbruvica)...
Read MoreVenetoclax-rituximab combination improves survival in patients with unresponsive and relapsed chronic lymphocytic leukemia
In a nutshell This study looked at the effectiveness of venetoclax-rituximab (Venclexta–Rituxan) in patients with unresponsive or relapsed chronic lymphocytic leukemia (CLL). Researchers found that this treatment improved survival in patients with CLL. Some background Chronic lymphocytic leukemia is a cancer of the bone marrow. This can...
Read MoreUsing steroid medication to prevent stem cell transplant complications in patients with leukemia
In a nutshell This study looked at the effects of using steroid medication to prevent complications after stem cell transplant and improve survival in patients with leukemia. Researchers found that low-dose steroids improved outcomes in these patients. Some background Leukemia is a cancer of the blood-forming tissues such as the bone...
Read MoreImproved survival in young patients with acute myeloid leukemia
In a nutshell This study evaluated the progress made in the survival of pediatric patients with acute myeloid leukemia (AML) in the Netherlands. Researchers concluded that recent progress in the treatment of AML has improved survival in this group of patients. Some background Acute myeloid leukemia (AML) is a cancer that can commonly affect...
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