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Allogenic hematopoietic stem cell transplant for patients with unresponsive acute myeloid leukemia

Posted by on Mar 20, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the effectiveness of allogeneic hemopoietic stem cell transplant (alloHSCT) in patients with unresponsive acute myeloid leukemia. This study concluded that alloHSCT is the best treatment option for these patients. Some background Patients with unresponsive acute myeloid leukemia (AML) are those...

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A long term follow-up study of young people with acute lymphoblastic leukemia.

Posted by on Mar 20, 2019 in Leukemia | 0 comments

In a nutshell This study examined the long-term effectiveness of different treatment strategies for acute lymphoblastic leukemia (ALL) in young people. This study concluded that augmented treatment for rapid early responders was most beneficial, with improved survival at 10 years.  Some background ALL is a cancer of the bone marrow. It leads to...

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Could hyperbaric oxygen therapy improve umbilical cord blood transplantation outcomes?

Posted by on Mar 20, 2019 in Leukemia | 0 comments

In a nutshell This study examined if hyperbaric oxygen therapy is safe and can improve outcomes in umbilical cord blood transplantation. This study concluded that the use of hyperbaric oxygen therapy before umbilical cord blood transplantation is safe and can improve outcomes in certain patients.   Some background Stem cells allow the production...

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Infections after treatment in children with acute leukemia

Posted by on Mar 16, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the occurrence of infections in children with acute lymphoblastic leukemia or acute myeloid leukemia patients that have completed treatment. This study concluded that infections are a common complication after treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) and acute myeloid...

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Long-term effectiveness of tyrosine kinase inhibitors for newly diagnosed chronic-phase chronic myeloid leukemia

Posted by on Mar 16, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the long-term safety and effectiveness of tyrosine kinase inhibitors for chronic-phase chronic myeloid leukemia. This study concluded that the outcomes for these patients are satisfactory and reliable. Some background Patients with chronic phase chronic myeloid leukemia (CP-CML) generally have mild...

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Is entospletinib an effective treatment for relapsed or unresponsive chronic lymphocytic leukemia?

Posted by on Mar 12, 2019 in Leukemia | 0 comments

In a nutshell This study examined if entospletinib can be used as a treatment for relapsed or unresponsive chronic lymphocytic leukemia (CLL). This study concluded entospletinib has disease reducing activity in patients with CLL, where previous treatment has failed. Some background Chronic lymphocytic leukemia (CLL) is a cancer of the bone marrow. It...

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Effectiveness of venetoclax in patients with unresponsive chronic lymphocytic leukemia

Posted by on Mar 9, 2019 in Leukemia | 0 comments

In a nutshell This study looked at the effectiveness of venetoclax (Venclexta) in the treatment of relapsed or unresponsive chronic lymphocytic leukemia (CLL). Researchers found venetoclax improved outcomes in these patients. Some background CLL is a cancer of the bone marrow. This may lead to an abnormal immune system. It is also often...

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Is ibrutinib alone, or combined with rituximab a more effective treatment for chronic lymphocytic leukemia?

Posted by on Feb 28, 2019 in Leukemia | 0 comments

In a nutshell This study examined if ibrutinib alone, or combined with rituximab is a more effective treatment for chronic lymphocytic leukemia (CLL). This study concluded that both treatments have similar survival, but adding rituximab to ibrutinib leads to faster remissions. Some background CLL is a cancer of the bone marrow. This leads to...

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Combining ibrutinib and umbralisib to treat relapsed/unresponsive chronic lymphocytic leukemia

Posted by on Feb 28, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of ibrutinib (Imbruvica) combined with umbralisib for patients with released/unresponsive chronic lymphocytic leukemia (CLL). This study concluded that the combination of umbralisib and ibrutinib is well tolerated and effective in relapsed/unresponsive CLL.  Some background...

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Treatment of childhood ALL with therapy to the spinal area

Posted by on Feb 28, 2019 in Leukemia | 0 comments

In a nutshell This study looked at the use of medication delivered to the spinal area (intrathecal) in patients with acute lymphoblastic leukemia (ALL). Researchers showed that this may be used instead of radiation to the head in these patients, with similar outcomes. Some background Acute lymphoblastic leukemia is a cancer of the immune system that...

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