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Adding inotuzumab ozogamicin with or without blinatumomab to chemotherapy for ALL.

Posted by on Nov 26, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the effectiveness of adding inotuzumab ozogamicin (Besponsa) and blinatumomab (Blincyto) to low-intensity chemotherapy in the treatment of ALL. Researchers found that this combination of treatment was effective in these patients. Some background Acute lymphoblastic leukemia (ALL) is a cancer of the bone marrow. This...

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Use of specific T-cells in the treatment of ALL

Posted by on Nov 25, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the use of specific T-cells to treat acute lymphoblastic leukemia. Researchers found that using these cells was effective in the treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) is a type of cancer of the bone marrow. This can lead to abnormal cells in the immune system. It is often...

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Is blinatumomab safe and effective in the treatment of ALL?

Posted by on Nov 25, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the safety and effectiveness of blinatumomab (Blincyto) in the treatment of unresponsive acute lymphoblastic leukemia (ALL). Researchers found that blinatumomab was safe and effective in the treatment of these patients. Some background Acute lymphoblastic leukemia is a type of cancer of the bone marrow. This can lead...

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Combinations of lenalidomide, fludarabine and rituximab for previously untreated chronic lymphocytic leukemia

Posted by on Nov 19, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of a combination of lenalidomide (Revlimid), fludarabine (Fludara) and rituximab (Rituxan) in patients with previously untreated chronic lymphocytic leukemia. This study concluded that this combination was effective, but the tolerability varied between...

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Imatinib combined with chemotherapy for patients with acute lymphoblastic leukemia

Posted by on Nov 10, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the effectiveness of chemotherapy combined with imatinib (Glivec) in the treatment of acute lymphoblastic leukemia (ALL) in patients with abnormal genes. Researchers found that this treatment was effective in this group of patients. Some background Acute lymphoblastic leukemia is a type of bone marrow cancer. This...

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Symptom burden for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors

Posted by on Oct 30, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the symptom burden on patients with chronic phase chronic myeloid leukemia (CP-CML) who were treated with second or third generation tyrosine kinase inhibitors. This study concluded that the side effects of this treatment may affect the quality of life for these patients. Some background Chronic myeloid...

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Comparing infection-related healthcare resource utilization and costs for patients with chronic myeloid leukemia patients treated with tyrosine kinase inhibitors

Posted by on Oct 30, 2018 in Leukemia | 0 comments

In a nutshell This study aimed to compare healthcare resource utilization and costs associated infections in patients with chronic myeloid leukemia patients receiving dasatinib and nilotinib. This study concluded that dasatinib use is associated with higher healthcare resource utilization and health care costs compared to nilotinib due to...

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NEW: Clinical guidelines for the diagnosis and treatment of chronic myeloid leukemia

Posted by on Oct 30, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the best clinical practice guidelines in the diagnosis and treatment of chronic myeloid leukemia (CML). The study found that management of CML should be guided by patient age, medical conditions, and side effects of the chosen drug. Some background Chronic myeloid leukemia is a cancer of the bone marrow. It results...

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Evaluating the safety of ibrutinib in leukemia and lymphoma

Posted by on Oct 20, 2018 in Leukemia | 0 comments

In a nutshell This study looked at the evidence for the safety of ibrutinib (Imbruvica) in the treatment of patients with chronic lymphocytic leukemia (CLL) or mantle cell lymphoma (MCL). Researchers found that this drug is safe to use in these patients. Some background Leukemia and lymphoma are types of cancer of the bone marrow. They can lead to...

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