In a nutshell This paper studied the performance of microsurgical testicular sperm extraction in patients with Klinefelter syndrome. Some background Klinefelter syndrome is caused by an abnormal number of chromosomes. This causes nonobstructive azoospermia (lack of sperm in semen). Klinefelter Syndrome is associated with infertility and...
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Ovarian stripping VS cystectomy – Which is better for treating ovarian endometriomas?
In a nutshell This paper compared ovarian stripping and cystectomy with regards to recurrence (return) of endometriosis and pregnancy. Some background Ovarian endometriomas occurs when endometrium tissue (tissue that lines the uterus) grows inside the ovary, away from its normal location. These endometriomas frequently require surgical...
Read MoreIs slight bleeding before menstruation associated with endometriosis?
In a nutshell This paper studied the association between premenstrual spotting and endometriosis in infertile women. Some background Endometriosis occurs when endometrial tissue (tissue that lines the inside of the uterus) grows outside of the uterus, causing pain and infertility. Currently, diagnosis of endometriosis is through visual inspection...
Read MoreWhat is the effect of oral contraceptive pills on women with polycystic ovarian syndrome?
In a nutshell This paper studied the various effects of oral contraceptive pills on women with polycystic ovarian syndrome. Some background Women with polycystic ovarian syndrome often have reduced fertility and exhibit male sex characteristics. Polycystic ovarian syndrom occurs when a womans hormones are out of balance, leading to enlarged...
Read MoreInvitation to a trial examining whether injecting human chorionic gonadotropin increases implantation rates in in vitro fertilization
In a nutshell This trial will examine whether introducing human chorionic gonadotropin into the uterus prior to implantation increases the success rate of in vitro fertilization. The effectiveness of this treatment will be measured through the implantation, pregnancy, and ongoing pregnancy rates. This trial is being conducted in Atlanta,...
Read MoreCan folate help in polycystic ovary syndrome?
In a nutshell This paper studied the effects of folate on indicators of inflammation and oxidative stress in women with polycystic ovarian syndrome. Some background Poylcystic ovarian syndrome occurse when cysts (capsules, typically filled with liquid) grow around the ovaries due to the woman's hormones being out of balance. It is...
Read MoreIs lifting heavy loads in work harmful to pregnancy?
In a nutshell This paper studied the association between women lifting heavy loads in work and preterm birth and fetal deaths. Some background Among pregnant women who work, many can be involved in physically demanding work and have to lift heavy weights. The risk of miscarriage (death of fetus) and preterm birth (birth before the 37th week...
Read MoreCan we predict insulin resistance in polycystic ovarian syndrome?
In a nutshell This paper studied the relationship between visceral adiposity index and other factors in women with polycystic ovarian syndrome. Some background Polycystic ovarian syndrome can cause anovulation (no release of eggs from body leading to infertility), irregular menstruations, and hyperandrogenemia (elevation of hormone that...
Read MoreMale hypogonadism – causes, diagnosis and treatment
In a nutshell This paper described the symptoms and treatment of male hypogonadism. Some background In males, the testes function to produce testosterone and sperm. Testosterone is crucial for the development of male sexual characteristics and spermatogenesis (production of sperm). Spermatogenesis is critical for male fertility. Male...
Read MoreWhich is better after a miscarriage? – surgery vs waiting
In a nutshell This paper compared the effectiveness and safety of expectant compared to surgical management of first-trimester (0-13 weeks) miscarriage (loss of fetus). Some background After a miscarriage, surgical evacuation is done to remove tissue and substances left behind in the uterus. It is associated with side effects such as...
Read MoreCan treating sleep disturbance increase testosterone levels?
In a nutshell This paper studied whether treating nocturia increased testosterone levels in men with hypogonadism (insufficient production of testosterone). Some background Nocturia (having to wake up and urinate at night) leads to sleep disturbances. This can affect testosterone (a sex hormone) secretion. Testosterone contributes to sperm...
Read MoreHow does inflammation of the epididymis affect sperm makeup?
In a nutshell This paper studied how acute epididymitis affected sperm composition. Some background Epididymitis (infection of the epididymis; a duct behind the testes through which sperm passes) can directly affect the epididymis and also the testes. Studies have shown that infections and inflammations contribute to male infertility. However,...
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