In a nutshell This study investigated if mild ovarian stimulation is as effective as conventional stimulation in vitro fertilization (IVF). They found that mild ovarian stimulation provides greater safety and lower cost, in addition to comparable success rates. Some background A part of the IVF process, women undergo a procedure to harvest...
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In a nutshell This study investigated if there is a link between ingestion of pesticide residues and the success of fertility treatment. They found that a greater intake of high pesticide residues is associated with a lower chance of achieving pregnancy and live birth in women undergoing fertility treatment. Some background Pesticides are...
Read MoreIn a nutshell The aim of this phase 4 trial is to assess if a single dose of a gonadotrophin-releasing hormone (GnRH) agonist enhances implantation during in vitro fertilization (IVF). The main outcome to be measured is the rate of live births. This study is being conducted in New Jersey, in the United States. The details In very early pregnancy,...
Read MoreIn a nutshell This phase 4 trial aims to evaluate if co-administration of a gonadotrophin releasing-hormone (GnRH) agonist improves oocycte maturity. The main outcome to be investigated is the number of mature oocytes. The details One of the important steps during in vitro fertilization (IVF) is stimulating the maturation of oocytes (eggs). GnRH...
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In a nutshell This study investigated the effects of medroxyprogesterone acetate (MPA) as an ovarian stimulant in women with endometriosis. They found that MPA was similarly effective as conventional COH protocol and was well tolerated. Some background Women undergoing fertility treatment may undergo controlled ovarian stimulation (COH). This...
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In a nutshell This study investigated whether endometriosis surgery impacted pregnancy rates as a result of in vitro fertilization (IVF). They found that the severe endometriosis resulted in lower IVF pregnancy rates and the optimal time for IVF is 7-25 months following endometriosis surgery. Some background Endometriosis is a chronic condition...
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In a nutshell This study investigated if the time between semen processing and intrauterine insemination (IUI) affected pregnancy outcomes. They found that the time interval between semen processing and IUI does not adversely affect pregnancy outcomes. Some background Intrauterine insemination (IUI) is a procedure whereby sperm are delivered...
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In a nutshell This study investigated if co-treatment with metformin improved fertility outcomes in patients with polycystic ovarian syndrome (PCOS). They found that metformin co-treatment was associated with a higher birth rate and higher pregnancy rates in PCOS patients. Some background Women with PCOS can experience fertility problems and may...
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In a nutshell This study looked at various markers of ovarian function in women who had experienced recurrent miscarriage. They found that women with an unexplained cause (idiopathic) of recurrent miscarriage had lower levels of anti-Mullerian hormone (AMH) and estradiol. Some background Recurrent miscarriage (RM) is a condition where a...
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You may not know this but you can get warnings from the FDA on problems with prescription medications and over-the-counter drugs. For example, on August 11, a FDA News Release issued this warning about over-the-counter liquid vitamins that are given to young children and those who cannot swallow pills. “The U.S. Food and Drug Administration is...
Read MoreIn a nutshell This study investigated if anti-Mullerian hormone (AMH) was associated with antral follicle count in women with polycystic ovarian conditions. They found that AMH levels were a reliable predictor of antral follicle count in these patients. Some background Anti-Mullerian hormone (AMH) is produced in the premature ovarian (antral)...
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In a nutshell This article examined the dietary habits of Asian males to determine if it had any impact on semen quality. The study concluded that a "Western diet", high in sugar and carbohydrates, was associated with lower semen quality. Some background Infertility is a growing problem and there is evidence that semen quality is...
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