In a nutshell This article reviewed different treatment options for couples experiencing infertility. Some background Infertility affects approximately 1 in 7 couples trying to conceive. Treatment of infertility depends on the cause. Men, women or both partners can have symptoms of infertility. In women, infertility can be due...
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Does growth hormone stimulation improve live birth outcomes in women with poor prognosis?
In a nutshell This study investigated if growth hormone stimulation (GHS) improves fertility outcomes in women with severe infertility. They found that GHS was associated with a higher live birth rate (LBR) in these women. Some background Infertility is a growing problem worldwide. Assisted reproductive technology (ART) is the only solution for...
Read MoreOmega-3 Fatty Acids For the New Year!
I’ve been eating a load of holiday foods and thinking that I’m going to need to make some dietary adjustments. Like me, you may have read or heard in the news that clinical trials looking at omega-3 fatty acids (omega-3 acid ethyl esters – O3AEE) did NOT significantly reduce major cardiovascular events. In fact, the news may have said that...
Read MoreDoes vitamin D increase conception in couples with infertility?
In a nutshell This study evaluated the effects of added vitamin D to margarine on the pregnancy rates of women with infertility. This study found that women with infertility who had extra vitamin D were more likely to become pregnant compared to women who were not. Some background Vitamin D is needed for calcium absorption and involved in bone...
Read MoreWhat is the evidence behind male fertility supplements?
In a nutshell This study looked at the ingredients of common male fertility supplements. This study found that most ingredients do not have evidence of improving male fertility. Some background Male factors are the sole cause of 20% of infertility cases and contribute to over 40% of infertility cases. Oxidative stress contributes to low sperm...
Read MoreDoes progestogen prevent pregnancy loss in women with recurrent miscarriages?
In a nutshell This study investigated the effect of progestogen (PG) in reducing the miscarriage risk. They found that PG may reduce miscarriage risk in women with a history of recurrent miscarriage (RMC). Some background Early pregnancy loss, or miscarriage, is most common in the first trimester. Women that have more than 3...
Read MoreCan sperm DNA fragmentation be used to assess infertility?
In a nutshell This study investigated if measuring sperm DNA fragmentation (SDF) is useful in male infertility. They found that high SDF was more common in older men with low sperm motility (SM). Some background Male infertility affects almost 50% of infertile couples. It is usually diagnosed by measuring semen parameters. These include sperm...
Read MoreDoes psychological therapy improve pregnancy rates in patients with infertility?
In a nutshell This review looked at psychological and mind-body therapies for patients with infertility. It found that mental health outcomes were improved following therapy. It also found that pregnancy rates were higher among patients receiving therapy. Some background Over 10% of couples of childbearing age have used...
Read MoreDoes a man’s weight affect fertility and his children’s early health?
In a nutshell This study investigated the effects of a man’s weight on his fertility and child health. This study found that overweight and obese men were less fertile, impacting pregnancy outcomes and early childhood weight. Some background Male infertility is involved in about 40 to 50% of infertility cases. However, most...
Read MoreInvestigating the effectiveness of a letrozole ‘step-up’ protocol for controlled ovarian stimulation
In a nutshell This study investigated the effect of a letrozole (Femara) step-up protocol (SUP) for controlled ovarian stimulation (COS). They found that a letrozole-SUP was as effective as standard COS protocol and less costly. Some background Unexplained infertility (UI) is increasingly common. Women with UI usually have a normal...
Read MoreDoes stress affect semen quality?
In a nutshell This study looked at semen quality and stress in healthy men. It found that higher levels of life stress were associated with lower semen quality. Some background Up to half of the infertility cases involve male infertility. An important factor in male fertility is semen quality. Semen quality includes the concentration of sperm, how...
Read MoreIs the thickness of the womb lining related to ectopic pregnancy risk?
In a nutshell This study compared women who had an ectopic pregnancy (EP) vs a normal pregnancy following in vitro fertilization (IVF). It found that a thick lining of the womb protects against EP, and pelvic surgery and tubal-related infertility are risk factors for EP. Some background Ectopic pregnancy (EP) is when an embryo implants somewhere other...
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