In a nutshell This trial will investigate the effect of exercise training programs to manage hypertension in patients with hypertension with or without type 2 diabetes (T2D). The main outcome will be the change in systolic blood pressure (SBP) after 3 months. The details Hypertension or high blood pressure (BP) is a common and serious condition....
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Searching for patients with pre-hypertension to test a probiotic treatment strategy
In a nutshell This study will investigate the effect of probiotics in the prevention of hypertension. The main outcome will be a change in blood pressure (BP) after 12 weeks of treatment. The details Hypertension is a common and serious condition. Managing blood pressure (BP) levels is very important. Uncontrolled high BP can lead to...
Read MoreLooking for patients with borderline hypertension to test a non-pharmacological treatment strategy
In a nutshell This phase clinical trial will investigate the effect of remote ischemic conditioning (RIC) in patients with borderline hypertension. The main outcome will be the change in blood pressure (BP) over 33 days. The details Hypertension or high blood pressure (BP) is a serious condition. Hypertension increases the risk of major events...
Read MoreLooking for patients with high blood pressure to test a combination of folic acid and a blood pressure-lowering medication
In a nutshell This study is examining the effectiveness of adding folic acid to enalapril maleate (Vasotec) for patients with high blood pressure. The main outcome that will be measured is the decrease in homocysteine levels, a marker of high blood pressure. The details High blood pressure or hypertension can lead to other illnesses...
Read MoreLooking for patients with high blood pressure to test a Chinese herbal medicine
In a nutshell This study is examining the effectiveness of a herbal Chinese traditional medicine for high blood pressure. The main outcome to be measured will be the change in blood pressure after 8 weeks. The details Hypertension can damage blood vessels, which can cause other health problems. These include stroke, heart attacks,...
Read MoreLooking for patients with high blood pressure to try a single-pill combination medication
In a nutshell This study is evaluating the safety and effectiveness of losartan (Cozaar) plus hydrochlorothiazide (Microzide) in a single tablet for treating high blood pressure. The main outcomes will be blood pressure control rate after treatment and the number of patients who experience side effects. The details High...
Read MoreLooking for patients with hypertension to try a long-acting medication (nifedipine GITS)
In a nutshell This study will evaluate the effectiveness of the nifedipine (Adalat) gastrointestinal therapeutic system (GITS) on lowering blood pressure in adults with hypertension. The main outcomes measured will be blood pressure levels at follow-up and the change in blood pressure from the beginning to the end of treatment. The details...
Read MoreDoes body weight fluctuation increase the risk of heart disease and mortality?
In a nutshell This study investigated the effect of body weight changes on the risk of cardiovascular disease (CVD) and mortality. They found that body weight changes were associated with a higher risk of CVD and mortality. Some background Bodyweight fluctuation (BWF; weight changes) is common. Many people undergo BWF and it can be driven by...
Read MoreCould anti-hypertensive medications reduce the risk of dementia and Alzheimer’s disease?
In a nutshell This study investigated if anti-hypertensive medications (AHMs) reduce the risk of dementia and Alzheimer’s disease (AD). They found that AHMs may reduce the risk of dementia. Some background Hypertension or high blood pressure (BP) is a common condition. Managing BP levels is important. If untreated, hypertension can...
Read MoreManaging hypertension – a community-based approach
In a nutshell This study investigated if a comprehensive care model (CCM) improves the management of hypertension. They found that a CCM improved blood pressure (BP) control and reduced the risk of cardiovascular disease (CVD). Some background Hypertension or high blood pressure (BP) is a common condition. High BP can increase the risk of...
Read MoreReviewing the effectiveness of first-line anti-hypertensive drugs
In a nutshell This study investigated the safety and effectiveness of anti-hypertensive (AHT) drugs used as a first-line treatment (FLT). They found that thiazide (or thiazide-like) diuretics (TD/TLDs) had better safety and effectiveness than other classes used as FLT. Some background Hypertension or high blood pressure (BP) is a very common...
Read MoreDoes exercise improve heart health and reduce mortality even in those with high blood pressure?
In a nutshell This study examined whether physical activity can help lower mortality risk and improve heart health in people with high blood pressure. This study concluded that physical activity reduced mortality risk, including those with high blood pressure. Some background According to the World Health Organization, hypertension (HT) or high...
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