In a nutshell This study examined whether closed-loop or “automated” delivery of insulin would be a suitable treatment for pregnant women with type-1 diabetes. The authors concluded that the closed-loop therapy successfully controlled blood-sugar levels during pregnancy, labor and delivery. Some background Type-1 diabetes (T1D) occurs...
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Is insulin degludec more effective than insulin glargine U100 at reducing hypoglycemia in patients with type 2 diabetes?
In a nutshell This study investigated the effects of insulin degludec (Tresiba) versus insulin glargine U100 (Lantus) on hypoglycemia (low blood sugar) in patients with type 2 diabetes. They found the number of hypoglycemic episodes was significantly lower in patients receiving insulin degludec. Some background Insulin therapy is a...
Read MoreEffect of protein on vildagliptin
In a nutshell This study investigated whether taking a protein supplement before a meal could improve the effectiveness of galvus (Vildagliptin) in people with type 2 diabetes (T2D). It found that vildagliptin was more effective when given with a protein ‘preload’. Some background Incretins are hormones that are made in the intestines...
Read MoreGuidelines on the management of diabetes in pregnancy
In a nutshell These guidelines presented recommendations for the management of diabetes in pregnancy. It was concluded that counselling before pregnancy, appropriate care during pregnancy, and follow-up after delivery is needed. Some background Diabetes in pregnancy is increasing in the United States. Most of this is due to gestational diabetes...
Read MoreContinuous glucose monitoring improves glycemic control in patients with type 1 diabetes
In a nutshell This study investigated the effect of continuous glucose monitoring (CGM) in managing blood sugar levels in patients with type 1 diabetes treated with multiple daily insulin injections. They found CGM resulted in a clinically meaningful improvement in glycemic (blood sugar) control. Some background Glycemic control is critical for...
Read MoreDexamethasone implant in patients with diabetic macular edema
In a nutshell This study examined the use of an Ozurdex (dexamethasone) implant in people with diabetic macular edema (DME). It determined that the implant improved vision in these patients. Some background DME is a common complication of diabetes. It is swelling in an area at the back of the eye called the macula. DME can result in visual...
Read MoreIs there an increased risk of epilepsy in patients with type 1 diabetes?
In a nutshell This study investigated if patients with type 1 diabetes have an increased risk of developing epilepsy. The authors concluded that patients with type 1 diabetess are three-times more likely to be diagnosed with epilepsy than the general population. Some background Type 1 diabetes (T1D) is a metabolic disease that over time can...
Read MoreEffects of carbohydrate consumption on luseogliflozin activity
In a nutshell This study compared the effects of Lusefi (luseogliflozin) in people with type 2 diabetes (T2D) who had different carbohydrate intakes. It determined that luseogliflozin reduced glucose levels, regardless of carbohydrate intake. Some background Luseogliflozin is an SGLT2 inhibitor. SGLT2 is a protein in the kidneys that is important...
Read MoreDoes omega-3 fatty acid supplementation affect kidney function in type 2 diabetes?
In a nutshell This study examined if Omega-3 fatty acid supplementation could improve kidney function in patients with diabetes and hypertriglyceridemia. They found that a daily dose of 4 grams of Omega-3 fatty acids improved kidney function in these diabetic patients. Some background A common complication of diabetes is kidney disease. If it is...
Read MoreComparing snacking to total fasting in basal rate tests
In a nutshell This study compared the effects of low-carbohydrate snacking and total fasting during basal rate testing in people with type 1 diabetes (T1D). It was determined that there was no effect on blood glucose levels or hypoglycemia (dangerously low blood glucose), but patients preferred snacking. Some background Insulin is the hormone...
Read MoreFactors affecting physical activity in children with type 1 diabetes
In a nutshell This study examined factors affecting physical activity in children and adolescents with type 1 diabetes (T1D). It was found that fear of hypoglycemia (dangerously low blood glucose) and diversity of parental physical activity had the greatest impact. Some background Children and adolescents are recommended to do at least 1 hour of...
Read MoreDoes diabetes-related distress affect self-care in patients with type 2 diabetes?
In a nutshell This study investigated if diabetes-related distress and depressive symptoms had an impact on self-care in patients with type 2 diabetes. They found that elevated distress reduced the level of self-care in these patients. Some background Type 2 diabetes is a chronic metabolic disease. Self-care is important to manage symptoms and...
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