In a nutshell The aim of this study was to examine if diabetes in a woman increases the risk of attention-deficit/hyperactivity disorder (ADHD) in their child. The main finding of the study was that there was in an increased risk of ADHD in a child when the mother had diabetes that required medication. Some background There are three main types...
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Searching for patients with type 2 diabetes to test the effectiveness of the drug semaglutide compared to other standard treatments
In a nutshell The aim of this study is to test the effectiveness of semaglutide (Ozempic) in the treatment of type 2 diabetes compared to other currently used treatments. The main outcome to be measured is the change in HbA1c (blood test measuring blood sugar control over 3 months). This study is being conducted in the United States. The details...
Read MoreLower fat diet associated with diabetic eye disease in type 1 diabetes
In a nutshell This study aimed to look at the differences in the diets of people with type 1 diabetes (T1D) with and without diabetic retinopathy (DR; eye damage). The main finding of the study was that a higher fat intake was associated with lower frequency of DR. Some background DR is a type of eye disease that can occur in patients with T1D. If it...
Read MoreThe effect of drugs that protect nerves in the early stage of diabetic eye disease
In a nutshell The aim of this study was to assess whether giving drugs that protect nerves (brimonidine and somatostatin) into the eye can prevent or stop nerve damage in the eye of patients with type 2 diabetes (T2D). The main finding of this study was these drugs protected patients with nerve damage in the eye from the disease worsening. Some...
Read MoreHow effective is self-management with empagliflozin in the treatment of type 2 diabetes?
In a nutshell This study aimed to see how effective intermittent use of empagliflozin (Jardiance) controlled by the patients is in the treatment of poorly controlled type 2 diabetes (T2D). The main finding of the study was that intermittent use of empagliflozin controlled blood sugars as effectively as those who take it every day. Some background...
Read MoreDPP-4 inhibitor use in type 2 diabetes and the risk of diabetic eye disease
In a nutshell This study aimed to investigate if the use of DPP-4 inhibitor drugs for the treatment of type 2 diabetes (T2D) was harmful or helpful in diabetic retinopathy (DR; eye disease). The main finding of this study was that DPP-4 inhibitors did not increase the overall risk of DR. Some background DPP-4 inhibitors (DPP4i) are a type drug used to...
Read MoreInsulin or enhanced oral anti-diabetic tablet therapy in uncontrolled type 2 diabetes?
In a nutshell The aim of this study was to investigate the effects of starting insulin therapy versus enhancing oral tablet therapy after failure with three oral anti-diabetic (OAD) tablets in patients with type 2 diabetes (T2D). The main finding of the study was that adding insulin after failure with three OADs was effective, however, it increased...
Read MoreThe effect of canagliflozin on fatty liver disease and insulin production in patients with type 2 diabetes
In a nutshell The aim of this study was to investigate the effect of canagliflozin (Invokana) on insulin secretion and action along with changes in liver fat deposits and weight loss in patients with type 2 diabetes (T2D). The main finding of the study was that canagliflozin improved insulin secretion and usage, increased weight loss and...
Read MoreIs long-acting and fast-acting insulin combination injection as safe and effective as taking each separately?
In a nutshell The aim of this study was to compare the effectiveness and safety of insulin degludec/insulin aspart (IDegAsp) combination once daily (OD) versus insulin glargine (IGlar) U100 OD+insulin aspart (IAsp) OD in patients with type 2 diabetes (T2D). The main finding of this study was that IDegAsp achieved similar blood sugar control and...
Read MoreHigh magnesium in the diet is associated with lower rates of heart disease in patients with type 2 diabetes
In a nutshell This study aimed to investigate the relationship between magnesium and the risk of heart disease in type 2 diabetes (T2D). The main finding of the study is that higher magnesium intake, a higher rate of magnesium removal from the body and higher blood magnesium levels were associated with lower rates of heart disease in T2D. Some...
Read MoreSearching for patients with type 2 diabetes to test the effect of the drug efpeglenatide on heart disease
In a nutshell This trial is examining the effect of different doses of efpeglenatide on reducing cardiovascular (CV) disease in patients with type 2 diabetes (T2D). The main outcome to be measured is the occurrence of heart attacks, strokes or death from either of these events. The details Patients with type 2 diabetes (T2D) have a high risk of CV...
Read MoreProstaglandin E1 and methylcobalamin treatment versus Prostaglandin E1 therapy alone for patients with diabetic nerve disease
In a nutshell The aim of this study was to compare combined prostaglandin E1 and methylcobalamin treatment against prostaglandin E1 alone in the treatment of diabetic peripheral neuropathy (DPN; nerve damage). The main finding of the study was that the combination of prostaglandin E1 and methylcobalamin was better...
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