In a nutshell This study investigated the effect of smoking on acute coronary syndrome (ACS). They found that smoking was associated with lower mortality. Some background Smoking is a known cause of heart disease. Smoking leads to an increase in atherosclerotic plaques (fatty deposits) in the arteries. Acute coronary syndrome (ACS) is a term...
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How important is it to take medications after a heart attack?
In a nutshell The purpose of this study was to see how good patients are at actually taking their medications properly after a heart attack. The study also looked at the relationship between taking them properly and further heart attacks and strokes. The main finding of the study was that taking these medications properly reduced the risk of death and...
Read MoreDoes drinking coffee increase the risk of heart disease?
In a nutshell The aim of this study was to see if people with certain genes (that make the body less effective at breaking down coffee) have an increased risk of heart disease when they regularly drink coffee. The main finding of the study was that heavy coffee drinking was associated with an increased risk of heart disease and this risk did not change...
Read MoreBiolimus-eluting vs. bare-metal stents: what are the long-term benefits after a heart attack?
In a nutshell This study investigated the long-term effectiveness of biolimus-eluting stents (BES) versus bare-metal stents (BMS) to treat heart attacks. They found that BES was linked to a reduced risk of major cardiac events (MACE) after 5 years. Some background Myocardial infarction (MI) or heart attack is a serious cardiac event. It is caused by...
Read MoreIs early intervention in acute coronary syndrome more successful?
In a nutshell This study investigated if early intervention in acute coronary syndrome (ACS) improves clinical outcomes (COs). They found that early intervention does not have an effect on long-term COs in ACS. Some background Coronary artery disease (CAD) is used to describe heart conditions caused by reduced blood flow. Acute coronary syndrome (ACS)...
Read MoreThe effect of the DASH diet on heart disease
In a nutshell The aim of this study is to evaluate the effect of the DASH (dietary approaches to stop hypertension) diet on heart disease, blood pressure and diabetes in patients with and without diabetes. The main finding of this study was that the DASH diet is associated with a decreased risk of heart disease and improves blood pressure in patients...
Read MoreThe effect of the DASH diet on heart disease
In a nutshell The aim of this study is to evaluate the effect of the DASH (dietary approaches to stop hypertension) diet on heart disease, blood pressure and diabetes in patients with and without diabetes. The main finding of this study was that the DASH diet is associated with a decreased risk of heart disease and improves blood pressure in patients...
Read MoreDoes optimism improve outcomes in patients with angina?
In a nutshell This study investigated if optimism was associated with better angina outcomes. They found that ‘very optimistic’ (VO) patients had fewer angina episodes and better QOL. Some background Coronary artery disease (CAD) is any condition affecting the blood supply to the heart. Angina is pain caused by reduced blood flow. It...
Read MoreThe effects of widening blood vessels on maximum blood flow to the heart in patients with coronary artery disease
In a nutshell This study aimed to investigate the effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) on maximum blood flow in patients with coronary artery disease (CAD). The main finding of the study was that these procedures stopped the decrease in maximum blood flow through the heart arteries. Some...
Read MoreSearching for patients with acute coronary syndrome to test a new treatment
In a nutshell This phase 3 trial will investigate the safety and effectiveness of CSL112 to prevent major adverse cardiac events (MACEs). The main outcome will be the time taken until the first MACE. The details Acute coronary syndrome (ACS) is one type of coronary artery disease (CAD). ACS is any condition that is caused by...
Read MoreAntidepressants after heart attack – what are the risks?
In a nutshell This study investigated if there are risks associated with antidepressant (ATD) use after a heart attack (myocardial infarction, MI). They found that ATD use was associated with higher mortality (death) risk after MI. Some background Myocardial infarction (MI) is the medical term for a heart attack. Antidepressants (ATDs) are used...
Read MoreHow effective and cost-efficient is ranolazine compared to other anti-angina drugs?
In a nutshell This study aimed to compare the effectiveness and cost of ranolazine compared to other anti-angina drugs. The main finding of the study was that ranolazine users had lower rates of coronary artery bypass grafting (CABG) and overall hospitalizations, but higher rates of percutaneous coronary intervention (PCI) and hospitalizations due to...
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