In a nutshell This study examined the appropriate dosage of oxaliplatin for use in hyperthermic intraperitoneal chemotherapy in colorectal cancer patients at risk for peritoneal metastasis. Some background Colorectal cancer that has spread to the peritoneum, the lining of the abdomen, generally has a poor prognosis, due to...
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In a nutshell This study evaluated epiregulin gene expression as a potential predictive marker of benefit from cetuximab therapy in the treatment of advanced colorectal cancer. Some background Colorectal cancer is cancer that affects the colon and the rectum, two components of the digestive system. Treatment depends on many things,...
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In a nutshell This study investigated the prognostic value of hypoxia-inducible factor-1a and hypoxia-inducible factor-2a and their association with different clinicopathological features in patients with colorectal cancer. Some background Cancer of the colon and rectum (colorectal cancer) is the third most prevalent malignancy worldwide....
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In a nutshell This study investigated the efficacy and safety of EZN-2208, an anti-cancer agent, in patients with advanced colorectal cancer. Some background Colorectal cancer is cancer in the colon and rectum that has high tendency to metastasize (spread into distant organs) or to spread locally. Cancer results from uncontrolled...
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In a nutshell This review analyzed recent research investigating the effects of aspirin on colorectal cancer outcomes. Some background Aspirin is a common anti-inflammatory drug often used to relieve pain and reduce fever. The anti-inflammatory properties of aspirin are associated with its ability to inhibit the actions of the enzyme...
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“I share my story and speak to save lives.” “I thought I was fully awake, but I wasn’t. I thought I was open to living…the reality is that even after diagnosis, I was not living fully awake. What I’m doing differently now is having this diagnosis, really putting it out there, and sharing life and what is going on.” Endurance In your...
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In a nutshell This study analyzed the incidence and risk of ureteral injuries following colorectal surgery. Some background Colorectal surgery is often required to treat cancer of the colon or the rectum. Although all surgeries carry an inherent risk, the ureters (thin tubes connecting the kidneys and the bladder) are especially vulnerable to...
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In a nutshell This study evaluated survival benefit with the use of oxaliplatin (Eloxatin) in relation to KRAS gene status among patients with metastatic colorectal cancer. Some background Metastatic colorectal cancer (cancer that has spread from the large intestine to distant organs and tissues) is often treated by a combination of chemotherapy...
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In a nutshell This study evaluated preoperative magnetic resonance imaging (MRI) in the evaluation of surgical margins among rectal cancer patients. Some background Surgical removal of the tumor is the optimal treatment in the case of local rectal cancer. Removal of the intact tumor, with surrounding tissue and lymph-nodes, without leaving behind...
Read MoreIn a nutshell This study evaluated the relapse-free survival and disease-free survival in patients with stage II colorectal cancer according to treatments received. Some background Stage II of colorectal cancer (CRC) represents a large tumor that invades the entire wall of the large intestine and potentially the nearby organs, but has not yet...
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In a nutshell This study evaluated whether surgery has an effect on aerobic performance in colorectal cancer patients. Some background Patients with colorectal cancer may suffer from reduced lean body mass (calculated by subtracting body fat weight from total body weight) that cannot be reversed nutritionally, a condition referred to as...
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Why do patients blog? Why do they reveal personal information and medical experiences on the Internet? 1) To Share Information Annette McKinnon, author of ‘Here’s Your Gold Watch, Rheutired,’ started her blog “to inform people about things I learned that seem obvious to me now, but were hard to learn.” Carolyn Thomas, author of “My Heart...
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