In a nutshell This study examines the survival rates of patients with mucinous adenocarcinoma colon cancer. Some background The gastrointestinal tract, which includes the colon and rectum, is lined with epithelial cells, which are in turn lined with a mucin membrane, or mucus, which adds lubrication to the cells an acts as an...
Read More
In a nutshell This meta-analysis (an analysis of data combined from several similar studies) compared the efficacy of radiofrequency ablation versus liver resection in patients with colorectal cancer liver metastases. Some background Colorectal cancer liver metastasis refers to cancer that has spread to the liver. Liver...
Read More
In a nutshell This study examined the frequency of detecting indeterminate lung lesions on CT of patients with colorectal cancer and investigated if PET/CT was useful in detecting the malignant cases. Some background Colorectal cancer staging describes the severity of one’s cancer based upon the size and extent of the primary tumor and...
Read More
In a nutshell This study explored whether laproscopic surgery following neoadjuvant chemoradiotherapy is superior to open surgery in rectal cancer patients. Some background Two types of surgery are commonly used in the treatment of colorectal cancer. In open surgery, one large incision is made, while in laproscopic surgery several...
Read More
In a nutshell This study examined the impact of emergency presentation on the outcomes of patients with node-negative colorectal cancer undergoing curative surgery. Some background Node-negative colorectal cancer is cancer that has not spread to the nearby lymph nodes. Curative surgery (surgical removal of all of the cancer cells)...
Read More
In a nutshell This phase 2 trial compared the efficacy of panitumumab and modified chemotherapy regimen (mFOLFOX6) compared to bevacizumab and mFOLFOX6 in patients with unresectable, metastatic colorectal cancer. Some background Unresectable metastatic colorectal cancer (mCRC) is cancer that has spread from the...
Read More
In a nutshell This study evaluated the effect of overexpression of integrin αv subunits in colorectal cancer prognosis (outcome). Some background Colorectal cancer is a form of cancer that affects the cells of the colon or the rectum. Cancer cells need an adequate supply of oxygen, nutrients and removal of waste products to...
Read More
In a nutshell The meta-analysis assessed whether a longer interval between the end of neo-adjuvant chemo-radiotherapy and surgery leads to better outcomes in treatment of rectal cancer. Some background Rectal cancer involves the final part of the large intestine, or rectum. The first choice for treatment of rectal cancer is usually surgery....
Read More
Smoking and Tobacco Products Sales in the News According to a review of the history of tobacco control in the US, by the CDC, the Journal of American Medical Association (JAMA) in 1950, provided the first evidential link of smoking to cancers and other diseases. It took 40 years for the Joint Commission on Accreditation of Healthcare Organizations (JCAHO)...
Read More
In a nutshell This study compared polyp and adenoma miss rates from full-spectrum endoscopy colonoscopy with those of standard colonoscopy in colorectal cancer screening. Some background Colonoscopy is one of many tests used to screen for cancer or adenomas (precancerous growths) in the colon or rectum. Although colonoscopy is the...
Read More
In a nutshell This study examined what constitutes an acceptable length of distal resection margin when performing sphincter saving surgery for rectal cancer in patients receiving preoperative chemo-radiotherapy. Some background A resection margin is the edge or border of normal tissue removed with a tumor during surgery. A...
Read MoreIn a nutshell This study investigated whether chemotherapy-induced neutropenia improves survival of patients with metastatic colorectal cancer. Some background Metastatic colorectal cancer is colorectal cancer that has spread to other parts of the body. For unresectable (cannot be surgically removed) metastatic colorectal cancer, chemotherapy is...
Read More
