In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
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Looking for participants to test a vaccine for the treatment of advanced colorectal cancer
In a nutshell This phase 1b trial is examining the effectiveness and safety of a vaccine treatment, ATP128, in the treatment of advanced colorectal cancer. The main outcome to be measured is the tumor response to the treatment and treatment toxicity. This trial is being conducted in Arizona and California, US. The details Colorectal cancer is the...
Read MoreLooking for patients with advanced colorectal cancer to test an experimental treatment
In a nutshell This phase 1/2 trial is examining the effectiveness of treatment with GB1275 alone or in combination with immunotherapy in patients with advanced solid tumors such as colorectal cancer. The main outcome to be measured will be dose toxicity and tumor response to the treatment. This study is being conducted in Tennessee and Texas, US. The...
Read MoreThe effects of maintenance vs intermittent therapy in the treatment of advanced colorectal cancer
In a nutshell This study investigated the effects of maintenance therapy (MT) compared to intermittent therapy (IT) for patients with metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that MT might improve the treatment of these patients. Some background Colorectal cancer is the second most common cancer...
Read MoreInternal selective radiotherapy improves the outcomes of patients with colorectal cancer liver metastasis
In a nutshell This study investigated the effectiveness of selective internal radiation therapy (SIRT) in the treatment of colorectal cancer liver metastasis (CRC-LM). Researchers suggested that adding this therapy to the treatment improves the outcomes of the treatment. Some background The liver is a common site for colorectal cancer metastasis...
Read MoreMRI prognostic parameters in tailoring treatment for locally advanced rectal cancer
In a nutshell This study investigated the use of MRI predictive results to decide the best treatment for patients with locally advanced rectal cancer (LARC). Researchers suggested that early MRI results should be used in the treatment decision making. Some background Colorectal cancer is the third most common cancer in the world. Patients with LARC...
Read MoreLaparoscopic surgery is associated with improved quality of life in patients with colorectal cancer
In a nutshell This study investigated the quality of life of patients with colorectal cancer treated with surgery. Researchers suggested that laparoscopic surgery (LS) is associated with an improved quality of life. Some background The standard treatment for colorectal cancer is open surgery or LS. LS consists in inserting a tube with a camera through...
Read MoreAbdominal symptoms affecting the quality of life after surgery for colon cancer
In a nutshell This study compared abdominal (stomach/intestinal) symptoms (AS) between patients with colorectal cancer after colon surgery and after rectal surgery. Researchers suggested that complaints between both groups of patients are similar. Some background Colorectal cancer survivors often have long-term side effects from the cancer and its...
Read MoreSearching for patients with advanced colorectal cancer to test a new combination therapy
In a nutshell This phase 1b/2 trial will investigate the safety of cabozantinib (Cabometyx) with atezolizumab (Tecentriq) in patients with advanced solid tumors. The main outcomes will be the maximum tolerated dose (MTD) and overall response rate (ORR). The details Advanced cancers have limited treatment options. Surgery may not be possible. In many...
Read MoreTumor budding as a prognostic factor for treatment outcomes in patients with stage 2 colon cancer
In a nutshell This study investigated the role of tumor budding (TB) in predicting the best treatment for stage 2 colon cancer. Researchers suggested that TB could improve the effect of chemotherapy after surgery in these patients. Some background Stage 2 colorectal cancer accounts for one-third of patients who undergo curative surgery. Prognostic...
Read MoreOccupational therapy improves the quality of life of colorectal cancer survivors
In a nutshell This study investigated the effects of a healthy lifestyle (HL) in the quality of life of colorectal cancer survivors. Researchers suggested that a HL may improve the quality of life of these patients. Some background Colorectal cancer has become one of the most common cancers in the world. Given the effectiveness of the treatment and...
Read MoreLooking for participants with advanced colorectal cancer to test a new immunotherapy
In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...
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